Autoimmune cholangiopathy associated with rheumatoid arthritis

H. Ogata, H. Tsuji, M. Hashiguchi, K. Azuma, J. Shimono, M. Fujishima

研究成果: ジャーナルへの寄稿学術誌査読

3 被引用数 (Scopus)


We herein describe a patient with autoimmune cholangiopathy complicated with rheumatoid arthritis. A 58-year-old female was admitted to our hospital due to complications of arthralgia in her fingers, shoulders, elbows, knees and ankles. She presented with abnormally elevated levels of transaminases, alkaline phosphatase and was also negative for hepatitis B virus, hepatitis C virus and the serum mitochondrial antibody test, but had high titers of serum antinuclear antibody, rheumatoid factor and rheumatoid arthritis hemagglutination. A liver biopsy specimen showed chronic non-suppurative destructive cholangitis. She was thus diagnosed to have autoimmune cholangiopathy and rheumatoid arthritis. She began treatment with predonisolone 40mg per day. After 20 days of steroid therapy, her hepatic function tests improved and the arthralgia symptoms disappeared. This is, to our knowledge, the first case of autoimmune cholangiopathy associated with rheumatoid arthritis, in which both symptoms improved with steroid therapy.

出版ステータス出版済み - 2000

!!!All Science Journal Classification (ASJC) codes

  • 肝臓学
  • 消化器病学


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