Asymmetric Reduction of α-Methyl β-Keto Esters by Microbial Cells Immobilized with Prepolymer

Hiroyuki Akita; Hiroko Matsukura; Takeshi Oishi; Atsuo Tanaka; Kenji Sonomoto

doi:10.1248/cpb.35.4985

Asymmetric Reduction of α-Methyl β-Keto Esters by Microbial Cells Immobilized with Prepolymer

Hiroyuki Akita
, Hiroko Matsukura
, Takeshi Oishi
, Atsuo Tanaka
, Kenji Sonomoto

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

6 被引用数 (Scopus)

抄録

Asymmetric reduction of a-methyl β-keto esters using microbial cells immobilized by the prepolymer method was examined. It was found that by a proper selection of the prepolymer in the stage of immobilization, the chemical and optical yields were both improved appreciably in some cases compared to those obtained by reduction with the native microorganisms.

本文言語	英語
ページ（範囲）	4985-4987
ページ数	3
ジャーナル	Chemical and Pharmaceutical Bulletin
巻	35
号	12
DOI	https://doi.org/10.1248/cpb.35.4985
出版ステータス	出版済み - 1987
外部発表	はい

!!!All Science Journal Classification (ASJC) codes

化学一般
創薬

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10.1248/cpb.35.4985

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title = "Asymmetric Reduction of α-Methyl β-Keto Esters by Microbial Cells Immobilized with Prepolymer",

abstract = "Asymmetric reduction of a-methyl β-keto esters using microbial cells immobilized by the prepolymer method was examined. It was found that by a proper selection of the prepolymer in the stage of immobilization, the chemical and optical yields were both improved appreciably in some cases compared to those obtained by reduction with the native microorganisms.",

author = "Hiroyuki Akita and Hiroko Matsukura and Takeshi Oishi and Atsuo Tanaka and Kenji Sonomoto",

year = "1987",

doi = "10.1248/cpb.35.4985",

language = "English",

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AU - Akita, Hiroyuki

AU - Matsukura, Hiroko

AU - Oishi, Takeshi

AU - Tanaka, Atsuo

AU - Sonomoto, Kenji

PY - 1987

Y1 - 1987

N2 - Asymmetric reduction of a-methyl β-keto esters using microbial cells immobilized by the prepolymer method was examined. It was found that by a proper selection of the prepolymer in the stage of immobilization, the chemical and optical yields were both improved appreciably in some cases compared to those obtained by reduction with the native microorganisms.

AB - Asymmetric reduction of a-methyl β-keto esters using microbial cells immobilized by the prepolymer method was examined. It was found that by a proper selection of the prepolymer in the stage of immobilization, the chemical and optical yields were both improved appreciably in some cases compared to those obtained by reduction with the native microorganisms.

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UR - https://www.scopus.com/pages/publications/84966063463#tab=citedBy

U2 - 10.1248/cpb.35.4985

DO - 10.1248/cpb.35.4985

M3 - Article

AN - SCOPUS:84966063463

SN - 0009-2363

VL - 35

SP - 4985

EP - 4987

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 12

ER -

Asymmetric Reduction of α-Methyl β-Keto Esters by Microbial Cells Immobilized with Prepolymer

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!!!All Science Journal Classification (ASJC) codes

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