Asymmetric [2,3]-Wittig rearrangement as a general tool for asymmetric synthesis

Takeshi Nakai, Katsuhiko Tomooka

研究成果: ジャーナルへの寄稿学術誌査読

81 被引用数 (Scopus)

抄録

Recent advances in the asymmetric [2,3]-Wittig rearrangement as a general tool for asymmetric synthesis of homoallylic alcohols are described. First, the synthetic utilities of the asymmetric transmission type and the two asymmetric induction types are demonstrated, including applications in asymmetric syntheses of natural products and steroid side chains. Second, some examples are presented of the enantioselective versions involving a chiral ligand-bound boron enolate and organolithium as the migrating terminus. Finally, the mechanistic grounds of the asymmetric versions are discussed on the basis of the stereochemical analyses of the asymmetric version involving an enantiomerically-defined carbanion terminus.

本文言語英語
ページ(範囲)595-600
ページ数6
ジャーナルPure and Applied Chemistry
69
3
DOI
出版ステータス出版済み - 3月 1997
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 化学一般
  • 化学工学一般

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