TY - JOUR
T1 - Association of second-hand smoke exposure, quantified by salivary cotinine, with dental caries in Japanese adolescents
AU - Takao, Naohiro
AU - Furuta, Michiko
AU - Takeshita, Toru
AU - Kageyama, Shinya
AU - Goto, Takuro
AU - Zakaria, Myrna N.
AU - Takeuchi, Kenji
AU - Yamashita, Yoshihisa
N1 - Publisher Copyright:
© 2023 Nihon University School of Dentistry.
PY - 2023
Y1 - 2023
N2 - Purpose: Second-hand smoke has adverse effects on oral health. This cohort study used a multilevel approach to investigate the association of second-hand smoke exposure, as determined by salivary cotinine level, with dental caries in adolescents. Methods: Data from 75 adolescents aged 11 or 12 years and 2,061 teeth without dental caries were analyzed in this study. Annual dental exami-nations to assess dental caries were conducted between 2018 and 2021. Salivary cotinine and Dentocult SM-Strip level were measured at baseline. Information on the smoking habits of parents, snack frequency, regular dental visits, and use of fluoride toothpaste was collected at baseline from parent-reported questionnaires. Results: During the 3-year follow-up, dental caries was noted in 21 adolescents and 43 teeth. Participants exposed to parental smoking had higher salivary cotinine levels than those whose parents did not smoke. The multilevel Cox regression model showed that a high salivary cotinine level was associated with the incidence of dental caries, after adjusting for potential confounding factors (hazard ratio, 3.39; 95% confidence interval 1.08-10.69). Conclusion: This study suggests that the risk of dental caries is higher for adolescents who have high salivary cotinine levels attributable to second-hand smoke exposure.
AB - Purpose: Second-hand smoke has adverse effects on oral health. This cohort study used a multilevel approach to investigate the association of second-hand smoke exposure, as determined by salivary cotinine level, with dental caries in adolescents. Methods: Data from 75 adolescents aged 11 or 12 years and 2,061 teeth without dental caries were analyzed in this study. Annual dental exami-nations to assess dental caries were conducted between 2018 and 2021. Salivary cotinine and Dentocult SM-Strip level were measured at baseline. Information on the smoking habits of parents, snack frequency, regular dental visits, and use of fluoride toothpaste was collected at baseline from parent-reported questionnaires. Results: During the 3-year follow-up, dental caries was noted in 21 adolescents and 43 teeth. Participants exposed to parental smoking had higher salivary cotinine levels than those whose parents did not smoke. The multilevel Cox regression model showed that a high salivary cotinine level was associated with the incidence of dental caries, after adjusting for potential confounding factors (hazard ratio, 3.39; 95% confidence interval 1.08-10.69). Conclusion: This study suggests that the risk of dental caries is higher for adolescents who have high salivary cotinine levels attributable to second-hand smoke exposure.
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U2 - 10.2334/josnusd.22-0388
DO - 10.2334/josnusd.22-0388
M3 - Article
C2 - 36990753
AN - SCOPUS:85151224417
SN - 1343-4934
VL - 65
SP - 107
EP - 110
JO - Journal of Oral Science
JF - Journal of Oral Science
IS - 2
ER -