Antioxidant effects of methanol extracts from the heartwood of 23 Papua New Guinea (PNG) wood species were examined. The extract of Amoora sp. (Meliaceae) showed the strongest antioxidant activity against lipid peroxidation in rabbit erythrocyte membrane and linoleic acid autoxidation. Also, the extract of Amoora sp. showed potent 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity. These results showed that the heartwood of Amoora sp. is a possible source of antioxidative agents. The result of antioxidant activity-guided fractionation suggested that gallic acid, protocatechuic acid, and hydrolyzable tannins in the extract of Amoora sp. caused the potent antioxidant activity.
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