TY - JOUR
T1 - Anti-neurofascin 155 antibody-positive neuropathy in a human immunodeficiency virus-infected patient
AU - Okubo, So
AU - Mano, Tatsuo
AU - Sudo, Atsushi
AU - Goto, Ryoji
AU - Yano, Satoka
AU - Hara, Manato
AU - Ishiura, Hiroyuki
AU - Satake, Wataru
AU - Yanagimoto, Shintaro
AU - Ogata, Hidenori
AU - Toda, Tatsushi
N1 - Publisher Copyright:
© 2024 Japanese Society of Internal Medicine. All rights reserved.
PY - 2024
Y1 - 2024
N2 - Human immunodeficiency virus (HIV)-Associated neuropathy is a common complication of HIV infection and has several clinical subtypes. HIV-Associated chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a demyelinating neuropathy whose clinical features are known to differ from those of CIDP in the HIV-uninfected population. We herein report a case of CIDP in an HIV-infected patient who was finally diagnosed with anti-neurofascin 155 (NF155) antibody-positive neuropathy. The clinical features, including clinical findings and therapeutic responses, were typical of paranodal antibody-mediated neuropathy. To our knowledge, this is the first case of anti-NF155 antibody-Associated neuropathy in an HIV-infected patient.
AB - Human immunodeficiency virus (HIV)-Associated neuropathy is a common complication of HIV infection and has several clinical subtypes. HIV-Associated chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a demyelinating neuropathy whose clinical features are known to differ from those of CIDP in the HIV-uninfected population. We herein report a case of CIDP in an HIV-infected patient who was finally diagnosed with anti-neurofascin 155 (NF155) antibody-positive neuropathy. The clinical features, including clinical findings and therapeutic responses, were typical of paranodal antibody-mediated neuropathy. To our knowledge, this is the first case of anti-NF155 antibody-Associated neuropathy in an HIV-infected patient.
KW - Anti-neurofascin 155 antibody
KW - HIV-Associated neuropathy
KW - Peripheral neuropathy
UR - http://www.scopus.com/inward/record.url?scp=85185219144&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85185219144&partnerID=8YFLogxK
U2 - 10.2169/internalmedicine.1919-23
DO - 10.2169/internalmedicine.1919-23
M3 - Article
C2 - 37380455
AN - SCOPUS:85185219144
SN - 0918-2918
VL - 63
SP - 565
EP - 569
JO - Internal Medicine
JF - Internal Medicine
IS - 4
ER -