Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum

Jie Liu, Kuniyoshi Shimizu, Fumiko Konishi, Kiyoshi Noda, Shoichiro Kumamoto, Kenji Kurashiki, Ryuichiro Kondo

研究成果: ジャーナルへの寄稿学術誌査読

63 被引用数 (Scopus)

抄録

The ethanol extract of Ganoderma lucidum showed inhibitory activity on both isozymes (types 1 and 2) of 5α-reductase and suppression effects of ventral prostate growth induced by testosterone in castrated rat, but not induced by dihydrotestosterone. Activity-guided fractionation and TLC analysis suggested that the active principles in vivo were triterpenoids. These results indicate that the triterpenoids fraction of G. lucidum might be a useful ingredient in the treatment of benign prostatic hyperplasia.

本文言語英語
ページ(範囲)1691-1696
ページ数6
ジャーナルFood Chemistry
100
4
DOI
出版ステータス出版済み - 2007

!!!All Science Journal Classification (ASJC) codes

  • 分析化学
  • 食品科学

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