TY - GEN
T1 - Analyzing peptide adsorption states via nanowire-employed infrared spectrometry
AU - Naito, Hiroki
AU - Yasui, Takao
AU - Shimada, Taisuke
AU - Shioya, Nobutaka
AU - Shimoaka, Takafumi
AU - Tanaka, Masayoshi
AU - Nagasima, Kazuki
AU - Okochi, Mina
AU - Yanagida, Takeshi
AU - Hasegawa, Takeshi
AU - Baba, Yoshinobu
N1 - Funding Information:
This work was funded by ImPACT Program of Council for Science, Technology and Innovation (Cabinet Office, Government of Japan)
Publisher Copyright:
© 2019 CBMS-0001.
PY - 2019
Y1 - 2019
N2 - Peptides optimally binding to solid surfaces are a promising candidate for adding bio-affinity, however, their binding states are not fully revealed. Herein, we realized a methodology for analyzing peptide adsorption states via employing nanowires and infrared (IR) p-polarized multiple-angle incidence resolution spectrometry (pMAIRS). Our methodology enabled to provide large crystalline surface for peptide adsorption, and enhance signal intensities. We found that a modelled peptide had different adsorption states among crystal axes. Analyzing peptide adsorption states can pave the way for controlling adsorbed states, and moreover, using full potentials of peptide.
AB - Peptides optimally binding to solid surfaces are a promising candidate for adding bio-affinity, however, their binding states are not fully revealed. Herein, we realized a methodology for analyzing peptide adsorption states via employing nanowires and infrared (IR) p-polarized multiple-angle incidence resolution spectrometry (pMAIRS). Our methodology enabled to provide large crystalline surface for peptide adsorption, and enhance signal intensities. We found that a modelled peptide had different adsorption states among crystal axes. Analyzing peptide adsorption states can pave the way for controlling adsorbed states, and moreover, using full potentials of peptide.
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M3 - Conference contribution
AN - SCOPUS:85094964853
T3 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
SP - 1206
EP - 1207
BT - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PB - Chemical and Biological Microsystems Society
T2 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Y2 - 27 October 2019 through 31 October 2019
ER -