TY - JOUR
T1 - A successful resection and long-term survival of a patient with intrahepatic recurrences of combined hepatocellular-cholangiocarcinoma
T2 - Report of a case
AU - Eguchi, Hidetoshi
AU - Nagano, Hiroaki
AU - Sakon, Masato
AU - Miyamoto, Atsushi
AU - Kondo, Motoi
AU - Arai, Isao
AU - Morimoto, Osakuni
AU - Dono, Keizo
AU - Umeshita, Koji
AU - Nakamori, Shoji
AU - Wakasa, Kenichi
AU - Monden, Morito
N1 - Funding Information:
This study was partly supported by the CEA-DRF Remember project. X.K. received a Ph.D. fellowship from the MENESR. The UMR1136 (Université de Lorraine, INRA, IAM) is supported by the French National Research Agency (ANR) as part of the Investissements d’Avenir program (ANR-11-LABX-0002-01, Lab of Excellence ARBRE).
PY - 2002
Y1 - 2002
N2 - Because of the low incidence rate of combined hepatocellular-cholangiocarcinoma (combined HCC-CC), the clinicopathological features of a recurrent tumor of this disease remain to be elucidated. We describe a 47-year-old Japanese woman with a 5-cm diameter mass lesion in the liver. A hepatectomy and dissection of the local lymph nodes were performed and a histological examination of the resected specimen showed combined HCC-CC. After a follow-up of 15 months, intrahepatic recurrence was observed, and a hepatectomy was performed again followed by hepatic arterial infusion chemotherapy. A histological examination revealed that the recurrent tumors consisted of only cholangioacarcinoma. A disease-free survival was obtained for about 7 years after the recurrence. To improve the poor prognosis of combined HCC-CC, clinicopathological features of this disease and the therapy selection for recurrent tumors should be discussed.
AB - Because of the low incidence rate of combined hepatocellular-cholangiocarcinoma (combined HCC-CC), the clinicopathological features of a recurrent tumor of this disease remain to be elucidated. We describe a 47-year-old Japanese woman with a 5-cm diameter mass lesion in the liver. A hepatectomy and dissection of the local lymph nodes were performed and a histological examination of the resected specimen showed combined HCC-CC. After a follow-up of 15 months, intrahepatic recurrence was observed, and a hepatectomy was performed again followed by hepatic arterial infusion chemotherapy. A histological examination revealed that the recurrent tumors consisted of only cholangioacarcinoma. A disease-free survival was obtained for about 7 years after the recurrence. To improve the poor prognosis of combined HCC-CC, clinicopathological features of this disease and the therapy selection for recurrent tumors should be discussed.
UR - https://www.scopus.com/pages/publications/0036041245
UR - https://www.scopus.com/pages/publications/0036041245#tab=citedBy
U2 - 10.1007/s005950200140
DO - 10.1007/s005950200140
M3 - Article
C2 - 12181730
AN - SCOPUS:0036041245
SN - 0941-1291
VL - 32
SP - 742
EP - 746
JO - Surgery Today
JF - Surgery Today
IS - 8
ER -