A nuclear factor which interacts with an at-cluster in the first intron of rat α2-macroglobulin gene

Takashi Ito; Yoshiyuki Sakaki

doi:10.1016/0006-291X(87)91004-7

A nuclear factor which interacts with an at-cluster in the first intron of rat α₂-macroglobulin gene

Takashi Ito
, Yoshiyuki Sakaki

生体制御学

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

3 被引用数 (Scopus)

抄録

We have identified a nuclear protein which binds specifically to the first intron of rat α₂-macroglobulin gene. The protein became insoluble at low salt concentration retaining the binding specificity. Its molecular weight was estimated to be 22 kilodalton by a protein blotting procedure. The binding site of the protein determined by DNase I footprinting was an AT-strech which shared 80% homology with the cleavage consensus of Drosophila topoisomerase II.

本文言語	英語
ページ（範囲）	824-830
ページ数	7
ジャーナル	Biochemical and Biophysical Research Communications
巻	147
号	2
DOI	https://doi.org/10.1016/0006-291X(87)91004-7
出版ステータス	出版済み - 9月 15 1987

!!!All Science Journal Classification (ASJC) codes

生物理学
生化学
分子生物学
細胞生物学

文献へのアクセス

10.1016/0006-291X(87)91004-7

他のファイルとリンク

引用スタイル

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abstract = "We have identified a nuclear protein which binds specifically to the first intron of rat α2-macroglobulin gene. The protein became insoluble at low salt concentration retaining the binding specificity. Its molecular weight was estimated to be 22 kilodalton by a protein blotting procedure. The binding site of the protein determined by DNase I footprinting was an AT-strech which shared 80\% homology with the cleavage consensus of Drosophila topoisomerase II.",

author = "Takashi Ito and Yoshiyuki Sakaki",

note = "Funding Information: providing We would the nucleotide like to thank sequence Drs. Y. data, Tsuchiya and Misses and M. H. Hattori Hamada and for Y. Hayashi for assistance in preparation of the manuscript. This work was supported part by the Grant-in-Aid for Cancer Research from the Ministry of Education, Culture and Sciences (Japan).",

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