A multidisciplinary approach to soft-tissue sarcoma of the extremities

Robert Nakayama, Tomoaki Mori, Yusuke Okita, Yutaka Shiraishi, Makoto Endo

研究成果: ジャーナルへの寄稿総説査読

5 被引用数 (Scopus)


Introduction: Soft-tissue sarcoma (STS) denotes a group of rare and highly heterogeneous malignant tumors of mesenchymal origin. Accurate histological diagnosis is critical for selecting appropriate treatment. Complete tumor resection is the primary treatment for STS, and the efficacies of radiotherapy and chemotherapy have been tested in the adjuvant setting to improve oncological outcomes. Because most STS lesions arise in the extremities, preserving limb function and managing limb impairment after radical local treatment represent significant challenges. Areas covered: This article reviews the current front-line treatments for patients with extremity STS and discusses the multidisciplinary team-based efforts needed to improve oncological outcomes and survivorship. Expert opinion: Given the rarity, variety, and complexity of STS, a multidisciplinary approach involving experts in various disciplines is vital for improving outcomes in patients ranging from diagnosis to survivorship. A major challenge is building a sustainable system in each region permitting all patients with extremity STS to be treated at high-volume centers with multidisciplinary teams dedicated to this rare and complex disease.

ジャーナルExpert Review of Anticancer Therapy
出版ステータス印刷中 - 2020

!!!All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 薬理学(医学)


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