(Chemical Equation Presented) Axial ligation of the heme moiety by a proximal imidazole group is observed in a novel cytochromec oxidase (CcO) active-site model 1 in which the copper ion is bound to a N-(2-hydroxyphenyl) imidazole moiety. Spectroscopic observations of 1 suggest the unique transformation of an initial heme-μ-peroxo-CuII species into a heme-superoxide/CuI intermediate in the course of the CcO oxygenation reaction at low temperature.
!!!All Science Journal Classification (ASJC) codes
- 化学 (全般)