A case showing effective radiotherapy for a radiation-induced glioblastoma

K. Fukui, T. Inamura, A. Nakamizo, K. Ikezaki, S. Inoha, K. Nakamura, A. Matsuzaki, M. Fukui

研究成果: ジャーナルへの寄稿学術誌査読

7 被引用数 (Scopus)


Radiation-induced glioblastoma is usually resistant to all treatments. We report a case with radiation-induced glioblastoma, in which radiotherapy was remarkably effective. A 14-year-old female with a history of acute lymphoblastic leukemia, at the age of 7, underwent 15 Gy of radiotherapy to the whole brain. She was admitted to our department due to the development of headache and nausea. Magnetic resonance imaging showed an irregularly enhanced mass in the left frontal lobe. Partial removal of the mass was performed and histological examination showed it to be glioblastoma with a high MIB-1 index. The patient underwent 40 Gy of local radiotherapy and chemotherapy with ACNU and Interferon-β for 2 years. The residual tumor disappeared after the radiotherapy, and her status is still "complete remissione", 29 months after the onset.

ジャーナルNeurological Surgery
出版ステータス出版済み - 2001

!!!All Science Journal Classification (ASJC) codes

  • 外科
  • 臨床神経学


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