抄録
C-Glycosides are metabolically stable mimics of natural O-glycosides and are expected to be useful tools for investigation of the biological functions of glycans. Here, we describe the synthesis of a series of aryl and vinyl C-glycosides by stereoinvertive sp3-sp2 cross-coupling reactions of 2-deoxyglycosyl boronic acid derivatives with aryl or vinyl halide, mediated by a photoredox/nickel dual catalytic system. Hydrogenation of the vinyl C-glycosides afforded C-linked 2′-deoxydisaccharide analogues.
本文言語 | 英語 |
---|---|
ページ(範囲) | 1940-1944 |
ページ数 | 5 |
ジャーナル | Organic letters |
巻 | 23 |
号 | 5 |
DOI | |
出版ステータス | 出版済み - 3月 5 2021 |
!!!All Science Journal Classification (ASJC) codes
- 生化学
- 物理化学および理論化学
- 有機化学