附属胸部疾患研究施設

研究成果

年別の研究成果 1983 2004 2005 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2023

• 483 学術誌
• 40 総説
• 8 レター
• 4 編集
• 4 その他
  • 3 コメント/討論
  • 1 章

年別の研究成果

年別の研究成果

検索結果

• 2023

  Exploratory mass cytometry analysis reveals immunophenotypes of cancer treatment-related pneumonitis

  Yanagihara, T., Hata, K., Matsubara, K., Kunimura, K., Suzuki, K., Tsubouchi, K., Ikegame, S., Baba, Y., Fukui, Y. & Okamoto, I., 2023, In: eLife. 12

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Analysis 100%
  • Pneumonia 100%
  • Cancer Treatment 100%
  • Immunity 100%
  • Lung 100%

• Impact of increased plasma levels of calreticulin on prognosis of patients with advanced lung cancer undergoing combination treatment of chemotherapy and immune checkpoint inhibitors

  Tsutsumi, H., Inoue, H., Shiraishi, Y., Hirayama, A., Nakanishi, T., Ando, H., Nakajima, M., Shinozaki, S., Ogata, H., Okamura, K., Kimura, S., Ogawa, T., ota, K., Yoneshima, Y., Tanaka, K., Hamada, N., Okamoto, I. & Iwama, E., 7月 2023, In: Lung Cancer. 181, 107264.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Patient 100%
  • Plasma 100%
  • Prognosis 100%
  • Lung Cancer 100%
  • Therapeutic Procedure 100%
  1 被引用数 (Scopus)

• Mass cytometry identifies characteristic immune cell subsets in bronchoalveolar lavage fluid from interstitial lung diseases

  Hata, K., Yanagihara, T., Matsubara, K., Kunimura, K., Suzuki, K., Tsubouchi, K., Eto, D., Ando, H., Uehara, M., Ikegame, S., Baba, Y., Fukui, Y. & Okamoto, I., 2023, In: Frontiers in Immunology. 14, 1145814.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Lung 100%
  • Interstitial Lung Disease 87%
  • Idiopathic Pulmonary Fibrosis 62%
  • T-Helper Cell 50%
  • Connective Tissue Disease 37%
  3 被引用数 (Scopus)

• MicroRNA-326 negatively regulates CD155 expression in lung adenocarcinoma

  Nakanishi, T., Yoneshima, Y., Okamura, K., Yanagihara, T., Hashisako, M., Iwasaki, T., Haratake, N., Mizusaki, S., ota, K., Iwama, E., Takenaka, T., Tanaka, K., Yoshizumi, T., Oda, Y. & Okamoto, I., 2023, (印刷中) In: Cancer Science.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Lung 100%
  • CD155 100%
  • MicroRNA 100%
  • Programmed Death 1 Receptor 30%
  • Programmed Death-Ligand 1 20%

• Regulation of PD-L1 expression in non–small cell lung cancer by interleukin-1β

  Hirayama, A., Tanaka, K., Tsutsumi, H., Nakanishi, T., Yamashita, S., Mizusaki, S., Ishii, Y., Ota, K., Yoneshima, Y., Iwama, E. & Okamoto, I., 2023, In: Frontiers in Immunology. 14, 1192861.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Cells 100%
  • Regulatory Mechanism 100%
  • Lung Cancer 100%
  • Interleukin 1 100%
  • Lung 100%

• Three-dimensional topological radiogenomics of epidermal growth factor receptor Del19 and L858R mutation subtypes on computed tomography images of lung cancer patients

  Ninomiya, K., Arimura, H., Tanaka, K., Chan, W. Y., Kabata, Y., Mizuno, S., Gowdh, N. F. M., Yaakup, N. A., Liam, C. K., Chai, C. S. & Ng, K. H., 6月 2023, In: Computer Methods and Programs in Biomedicine. 236, 107544.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Mutation 100%
  • Classification 100%
  • Computer Assisted Tomography 100%
  • Epidermal Growth Factor Receptor 100%
  • Patient 100%
  1 被引用数 (Scopus)

• TIP60 is required for tumorigenesis in non-small cell lung cancer

  Shibahara, D., Akanuma, N., Kobayashi, I. S., Heo, E., Ando, M., Fujii, M., Jiang, F., Prin, P. N., Pan, G., Wong, K. K., Costa, D. B., Bararia, D., Tenen, D. G., Watanabe, H. & Kobayashi, S. S., 6月 2023, In: Cancer Science. 114, 6, p. 2400-2413 14 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Cell Culture 100%
  • Development 50%
  • Growth 50%
  • Mouse 50%
  • Cancer Cell 50%
• 2022

  A multicenter, open-label, single-arm study of anamorelin (ONO-7643) in patients with cancer cachexia and low body mass index

  Naito, T., Uchino, J., Kojima, T., Matano, Y., Minato, K., Tanaka, K., Mizukami, T., Atagi, S., Higashiguchi, T., Muro, K., Takayama, K., Furuse, J., Morishima, E., Takiguchi, T. & Tamura, K., 5月 15 2022, In: Cancer. 128, 10, p. 2025-2035 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Body Mass Index 100%
  • Cachexia 100%
  • Anorexia 85%
  • Patient 71%
  • Body Weight 71%
  14 被引用数 (Scopus)

• A Multicenter, Randomized Phase III Study Comparing Platinum Combination Chemotherapy Plus Pembrolizumab With Platinum Combination Chemotherapy Plus Nivolumab and Ipilimumab for Treatment-Naive Advanced Non–Small Cell Lung Cancer Without Driver Gene Alterations: JCOG2007 (NIPPON Study)

  Shiraishi, Y., Hakozaki, T., Nomura, S., Kataoka, T., Tanaka, K., Miura, S., Sekino, Y., Ando, M., Horinouchi, H., Ohe, Y. & Okamoto, I., 6月 2022, In: Clinical Lung Cancer. 23, 4, p. e285-e288

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Cells 100%
  • Chemotherapy 100%
  • Patient 75%
  • Platinum 75%
  • Combination Chemotherapy 75%
  5 被引用数 (Scopus)

• Corrigendum to ‘Gefitinib induction followed by chemoradiotherapy in EGFR-mutant, locally advanced non-small-cell lung cancer: LOGIK0902/OLCSG0905 phase II study’: [ESMO Open Volume 6, Issue 4, August 2021, 100191] (ESMO Open (2021) 6(4), (S2059702921001526), (10.1016/j.esmoop.2021.100191))

  Hotta, K., Saeki, S., Yamaguchi, M., Harada, D., Bessho, A., Tanaka, K., Inoue, K., Gemba, K., Shiojiri, M., Kato, Y., Ninomiya, T., Kubo, T., Kishimoto, J., Shioyama, Y., Katsui, K., Sasaki, J., Kiura, K. & Sugio, K., 8月 2022, In: ESMO Open. 7, 4, 100532.

  研究成果: ジャーナルへの寄稿 › コメント/討論 › 査読

  Open Access

  • Patient 100%
  • Toxicity 100%
  • Radiation Pneumonia 100%
  • Pneumonia 50%
  • Chemoradiotherapy 50%

• Differences in the spectrum of respiratory viruses and detection of human rhinovirus C in exacerbations of adult asthma and chronic obstructive pulmonary disease

  Kan-o, K., Washio, Y., Fujimoto, T., Shiroyama, N., Nakano, T., Wakamatsu, K., Takata, S., Yoshida, M., Fujita, M. & Matsumoto, K., 1月 2022, In: Respiratory Investigation. 60, 1, p. 129-136 8 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Asthma Exacerbation 100%
  • Adult 85%
  • Virus 71%
  • Patient 57%
  • Species 57%
  4 被引用数 (Scopus)

• 石綿を要因とする原発性肺がんの労災保険制度の申請に対する，医師の診療体制の現状と課題

  Fukujin, T., Hasegawa, K., Onishi, K., Migita, T., Kurita, E., Seto, T., Tanaka, K., Sawada, S., Suzuki, K. & Hamasaki, S., 2022, In: Japanese Journal of Lung Cancer. 62, 5, p. 371-376 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Physician 100%
  • Asbestos 100%
  • Asbestos Exposure 100%
  • Lung Cancer 75%
  • Patient 50%

• 肺がん患者における石綿健康被害に対する当事者意識の現状と課題

  Fukujin, T., Hasegawa, K., Onishi, K., Migita, T., Kurita, E., Seto, T., Tanaka, K., Sawada, S., Suzuki, K. & Hamasaki, S., 8月 20 2022, In: Japanese Journal of Lung Cancer. 62, 4, p. 311-316 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Asbestos Exposure 100%
  • Asbestos 62%
  • Patient 50%
  • Lung Cancer 50%
  • Health 50%
• 2021

  An open-label phase Ⅰ/Ⅱ a clinical trial of 11β-HSD1 inhibitor for Cushing's syndrome and autonomous cortisol secretion

  Oda, S., Ashida, K., Uchiyama, M., Sakamoto, S., Hasuzawa, N., Nagayama, A., Wang, L., Nagata, H., Sakamoto, R., Kishimoto, J., Todaka, K., Ogawa, Y., Nakanishi, Y. & Nomura, M., 6月 18 2021, (印刷前の電子出版) In: The Journal of clinical endocrinology and metabolism.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Patient 100%
  • Clinical Trial 75%
  • Cushing Syndrome 50%
  • Hydrocortisone Release 50%
  • Area under the Curve 37%

• Early postnatal allergic airway inflammation induces dystrophic microglia leading to excitatory postsynaptic surplus and autism-like behavior

  Saitoh, B. Y., Tanaka, E., Yamamoto, N., Kruining, D. V., Iinuma, K., Nakamuta, Y., Yamaguchi, H., Yamasaki, R., Matsumoto, K. & Kira, J. I., 7月 2021, In: Brain, Behavior, and Immunity. 95, p. 362-380 19 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Microglia 100%
  • Ovalbumin 100%
  • Pervasive Developmental Disorder 62%
  • Behavior (Neuroscience) 37%
  • Disks Large Homolog 4 37%
  16 被引用数 (Scopus)

• Emerging therapeutic targets for idiopathic pulmonary fibrosis: preclinical progress and therapeutic implications

  Yanagihara, T., Scallan, C., Ask, K. & Kolb, M. R. J., 2021, In: Expert Opinion on Therapeutic Targets. 25, 11, p. 939-948 10 p.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読

  • Fibrosing Alveolitis 100%
  • Drug 50%
  • Biological Marker 25%
  • Combination Therapy 25%
  • Disease Course 25%
  4 被引用数 (Scopus)

• Imaging changes and immune-checkpoint expression on t cells in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis

  Kotetsu, Y., Yanagihara, T., Suzuki, K., Ando, H., Eto, D., Hata, K., Arimura-Omori, M., Yamamoto, Y., Harada, E. & Hamada, N., 9月 2021, In: Biomedicines. 9, 9, 1231.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Sarcoidosis 100%
  • Patient 57%
  • T Cell 57%
  • Bronchoalveolar Lavage Fluid 57%
  • Lung 42%
  1 被引用数 (Scopus)

• Immune-checkpoint kinetics for T cells in anti-MDA5 positive interstitial lung disease

  Suzuki, K., Yanagihara, T., Matsumoto, K., Chong, S. G., Ando, H., Ide, M., Arimura-Omori, M., Hata, K. & Hamada, N., 1月 1 2021, In: Rheumatology (United Kingdom). 60, 1, p. E14-E16

  研究成果: ジャーナルへの寄稿 › レター › 査読

  Open Access
  1 被引用数 (Scopus)

• Incense smoke-induced oxidative stress disrupts tight junctions and bronchial epithelial barrier integrity and induces airway hyperresponsiveness in mouse lungs

  Yamamoto, N., Kan-o, K., Tatsuta, M., Ishii, Y., Ogawa, T., Shinozaki, S., Fukuyama, S., Nakanishi, Y. & Matsumoto, K., 12月 2021, In: Scientific reports. 11, 1, 7222.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Smoke 100%
  • Lung 27%
  • Respiratory Tract Allergy 27%
  • Macrophage 22%
  • Tight Junction 16%
  15 被引用数 (Scopus)

• Inhibition of PI3Kδ Differentially Regulates Poly I:C– and Human Metapneumovirus–Induced PD–L1 and PD–L2 Expression in Human Bronchial Epithelial Cells

  Ogawa, T., Kan-o, K., Shiota, A., Fujita, A., Ishii, Y., Fukuyama, S. & Matsumoto, K., 11月 25 2021, In: Frontiers in Immunology. 12, 767666.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Epithelial Cell 100%
  • Ligand 100%
  • Programmed Death 1 Ligand 1 100%
  • Interferon 90%
  • Programmed Death-Ligand 1 90%
  1 被引用数 (Scopus)

• Scedosporium apiospermum lung disease in a patient with nontuberculous mycobacteria

  Ogata, H., Harada, E. & Okamoto, I., 1月 2021, In: Respirology Case Reports. 9, 1, e00691.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Mycetoma 100%
  • Atypical Mycobacterium 80%
  • Patient 40%
  • Culture 40%
  • Infection 40%
  1 被引用数 (Scopus)

• The Association of Aging-Related Polymorphisms with Susceptibility to Lung Cancer: A Case-Control Study in a Japanese Population

  Furuie, H., Arimura-Omori, M., Hamada, N., Yanagihara, T. & Kiyohara, C., 4月 2021, In: Asian Pacific Journal of Cancer Prevention. 22, 4, p. 1279-1285 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Binding Protein 100%
  • Protein P53 100%
  • Telomere 83%
  • Aging 66%
  • Oligosaccharide 50%
  3 被引用数 (Scopus)
• 2020

  A measuring method for occupancy of immune checkpoint inhibitors in the cell surface

  Yanagihara, T., Tanaka, K. & Matsumoto, K., 6月 18 2020, In: Biochemical and Biophysical Research Communications. 527, 1, p. 213-217 5 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Monospecific Antibody 100%
  • Antibodies 100%
  • Cells 50%
  • Electric Potential 50%
  • Immunity 50%
  3 被引用数 (Scopus)

• Association between telomere-related polymorphisms and the risk of ipf and copd as a precursor lesion of lung cancer: Findings from the fukuoka tobacco-related lung disease (fold) registry

  FOLD Registry Group, 3月 1 2020, In: Asian Pacific Journal of Cancer Prevention. 21, 3, p. 667-673 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Fibrosing Alveolitis 100%
  • Chronic Obstructive Lung Disease 77%
  • Telomerase Reverse Transcriptase 44%
  • Case-Control Study 44%
  • Telomere 44%
  5 被引用数 (Scopus)

• Current models of pulmonary fibrosis for future drug discovery efforts

  Yanagihara, T., Chong, S. G., Vierhout, M., Hirota, J. A., Ask, K. & Kolb, M., 8月 2 2020, In: Expert Opinion on Drug Discovery. 15, 8, p. 931-941 11 p.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読

  • Lung Fibrosis 100%
  • Fibrosing Alveolitis 40%
  • Drug Discovery 40%
  • Drug 20%
  • Animal 20%
  24 被引用数 (Scopus)

• Demystifying morphomolecular alterations of vasculature in interstitial lung diseases

  Yanagihara, T. & Jones, K. D., 3月 1 2020, In: European Respiratory Journal. 55, 3, 1902446.

  研究成果: ジャーナルへの寄稿 › 編集 › 査読

  Open Access
  4 被引用数 (Scopus)

• Immune-checkpoint profiles for T cells in bronchoalveolar lavage fluid of patients with immune-checkpoint inhibitor-related interstitial lung disease

  Suzuki, K., Yanagihara, T., Matsumoto, K., Kusaba, H., Yamauchi, T., Ikematsu, Y., Tanaka, K., Otsubo, K., Inoue, H., Yoneshima, Y., Iwama, E., Arimura-Omori, M., Harada, E., Hamada, N., Okamoto, I. & Nakanishi, Y., 8月 1 2020, In: International immunology. 32, 8, p. 547-557 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Immunity 100%
  • Interstitial Lung Disease 83%
  • Lung 83%
  • Immune Checkpoint Inhibitor 66%
  • T Cell 50%
  16 被引用数 (Scopus)

• Inhibition of PI3Kδ Enhances Poly I:C-Induced Antiviral Responses and Inhibits Replication of Human Metapneumovirus in Murine Lungs and Human Bronchial Epithelial Cells

  Fujita, A., Kan-o, K., Tonai, K., Yamamoto, N., Ogawa, T., Fukuyama, S., Nakanishi, Y. & Matsumoto, K., 3月 11 2020, In: Frontiers in Immunology. 11, 432.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Polyinosinic Polycytidylic Acid 100%
  • 2 (6 Amino 9 Purinylmethyl) 5 Methyl 3 (2 Methylphenyl) 3h Quinazolin 4 One 91%
  • Cells 75%
  • Epithelial Cell 66%
  • Interferon 50%
  9 被引用数 (Scopus)

• Insights into pathogenesis and clinical implications in myositis-associated interstitial lung diseases

  Yanagihara, T. & Inoue, Y., 9月 1 2020, In: Current Opinion in Pulmonary Medicine. 26, 5, p. 507-517 11 p.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読

  • Myositis 100%
  • Interstitial Lung Disease 85%
  • Lung 85%
  • Pathogenesis 57%
  • Dermatomyositis 57%
  9 被引用数 (Scopus)

• Mycobacterium avium pleuritis with multiple nodules in the pleura

  Ogata, H., Harada, E., Takao, T., Ijichi, K., Hamada, N. & Matsumoto, K., 8月 1 2020, In: Respirology Case Reports. 8, 6, e00608.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Atypical Mycobacterium 100%
  • Pleurisy 100%
  • Culture 75%
  • Visceral Pleura 75%
  • Biopsy 50%
  1 被引用数 (Scopus)

• Pleuropulmonary paragonimiasis with multiple nodules in the pleura

  Ogata, H., Harada, E., Moriya, S., Fukuyama, S., Suzuki, K., Shiraishi, Y., Ando, H., Uryu, K., Shinozaki, S., Ide, M., Sakamoto, A., Nakanishi, T., Hamada, N., Yoneshima, Y., ota, K., Kouhashi, K., Tateishi, Y., Miyashita, Y., Oda, Y. & Matsumoto, K., 2020, In: Internal Medicine. 59, 15, p. 1879-1881 3 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Paragonimiasis 100%
  • Thoracoscopy 66%
  • Visceral Pleura 66%
  • Woman 33%
  • Patient 33%
  2 被引用数 (Scopus)

• The cardiovascular system in idiopathic pulmonary fibrosis

  Chong, S. G., Yanagihara, T. & Kolb, M. R. J., 2020, In: ERS Monograph. 2020, 9781849841191, p. 198-211 14 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Patient 100%
  • Cardiovascular System 100%
  • Comorbidity 66%
  • Development 33%
  • Association 33%
  1 被引用数 (Scopus)
• 2019

  Effects of cigarette smoke on barrier function and tight junction proteins in the bronchial epithelium: Protective role of cathelicidin LL-37

  Tatsuta, M., Kan-O, K., Ishii, Y., Yamamoto, N., Ogawa, T., Fukuyama, S., Ogawa, A., Fujita, A., Nakanishi, Y. & Matsumoto, K., 11月 9 2019, In: Respiratory Research. 20, 1, 251.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Cigarette Smoke 100%
  • Tight Junction 62%
  • Adherens Junction 37%
  • Glucocorticoid 37%
  • Occludin 37%
  68 被引用数 (Scopus)

• Identification of genomic alterations acquired during treatment with EGFR-TKIs in non-small cell lung cancer

  Kubo, N., Harada, T., Shiraishi, Y., Nosaki, K., Nakagaki, N., Takeshita, M., Ouchi, H., Iwama, E., Tanaka, K., Okamoto, I., Sasaki, H. & Nakanishi, Y., 2月 2019, In: Anticancer research. 39, 2, p. 671-677 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Epidermal Growth Factor Receptor 100%
  • Receptor Tyrosine Kinase Inhibitors 87%
  • Sample 12%
  • Development 12%
  • Mutation 12%
  1 被引用数 (Scopus)

• Periodontitis Is Associated with Chronic Obstructive Pulmonary Disease

  Takeuchi, K., Matsumoto, K., Furuta, M., Fukuyama, S., Takeshita, T., Ogata, H., Suma, S., Shibata, Y., Shimazaki, Y., Hata, J., Ninomiya, T., Nakanishi, Y., Inoue, H. & Yamashita, Y., 5月 1 2019, In: Journal of Dental Research. 98, 5, p. 534-540 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Chronic Obstructive Lung Disease 100%
  • Periodontitis 91%
  • Confounder 8%
  • Cohort Study 8%
  44 被引用数 (Scopus)

• Trends in the prevalence of airflow limitation in a general Japanese population: Two serial cross-sectional surveys from the Hisayama Study

  Ogata, H., Hirakawa, Y., Matsumoto, K., Hata, J., Yoshida, D., Fukuyama, S., Inoue, H., Kitazono, T., Ninomiya, T. & Nakanishi, Y., 3月 1 2019, In: BMJ open. 9, 3, e023673.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読

  Open Access

  • Airflow 100%
  • Prevalence 53%
  • Smoking 30%
  • Age 15%
  • Ethinylestradiol Plus Megestrol Acetate 15%
  4 被引用数 (Scopus)
• 2018

  Academia–industry Cooperation in the Medical Field: Matching Opportunities in Japan

  Tsuruya, N., Kawashima, T., Shiozuka, M., Nakanishi, Y. & Sugiyama, D., 11月 2018, In: Clinical Therapeutics. 40, 11, p. 1807-1812 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Specific Industry 100%
  • Academia 100%
  • Cooperation 58%
  • Japan 33%
  • Information 33%
  8 被引用数 (Scopus)

• An autopsy case of bird-related chronic hypersensitivity pneumonitis presenting with repeated acute exacerbation

  Mikumo, H., Yanagihara, T., Hamada, N., Hashisako, M., Ijichi, K., Suzuki, K., Harada, E., Shikada, Y., Oda, Y. & Nakanishi, Y., 1月 1 2018, In: Respiratory Medicine Case Reports. 24, p. 92-94 3 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Hypersensitivity Pneumonitis 100%
  • Usual Interstitial Pneumonia 100%
  • Woman 33%
  • Patient 33%
  • Specimen 33%
  7 被引用数 (Scopus)

• A novel combination therapy for human oxaliplatin-resistant colorectal cancer using oxaliplatin and coxsackievirus A11

  Wang, B., Ogata, H., Takishima, Y., Miyamoto, S., Inoue, H., Kuroda, M., Yamada, K., Hijikata, Y., Murahashi, M., Shimizu, H., Okazaki, T., Nakanishi, Y. & Tani, K., 11月 2018, In: Anticancer research. 38, 11, p. 6121-6126 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Oxaliplatin 100%
  • Enterovirus 75%
  • Colorectal Cancer 66%
  • Therapeutic Procedure 33%
  • Cancer Cell 25%
  7 被引用数 (Scopus)

• Anticancer drug treatment for advanced lung cancer with interstitial lung disease

  Otsubo, K., Okamoto, I., Hamada, N. & Nakanishi, Y., 7月 2018, In: Respiratory Investigation. 56, 4, p. 307-311 5 p.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読

  • Interstitial Lung Disease 100%
  • Lung Cancer 90%
  • Chemotherapy 60%
  • Patient 50%
  • Therapeutic Procedure 30%
  15 被引用数 (Scopus)

• A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors

  Hijikata, Y., Okazaki, T., Tanaka, Y., Murahashi, M., Yamada, Y., Yamada, K., Takahashi, A., Inoue, H., Kishimoto, J., Nakanishi, Y., Oda, Y., Nakamura, Y. & Tani, K., 1月 2018, In: PloS one. 13, 1, e0187878.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Protein 100%
  • Ring Finger 100%
  • Patient 83%
  • Inpatient 83%
  • Cyclophosphamide 83%
  12 被引用数 (Scopus)

• A randomised phase II trial of S-1 plus cisplatin versus vinorelbine plus cisplatin with concurrent thoracic radiotherapy for unresectable, locally advanced non-small cell lung cancer: WJOG5008L

  Sasaki, T., Seto, T., Yamanaka, T., Kunitake, N., Shimizu, J., Kodaira, T., Nishio, M., Kozuka, T., Takahashi, T., Harada, H., Yoshimura, N., Tsutsumi, S., Kitajima, H., Kataoka, M., Ichinose, Y., Nakagawa, K., Nishimura, Y., Yamamoto, N. & Nakanishi, Y., 9月 11 2018, In: British journal of cancer. 119, 6, p. 675-682 8 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Arm 100%
  • Patient 50%
  • Cisplatin 41%
  • Overall Survival 33%
  • Radiation Therapy 25%
  24 被引用数 (Scopus)

• Association of nephrotoxicity during platinum-etoposide doublet therapy with UGT1A1 polymorphisms in small cell lung cancer patients

  Anai, S., Iwama, E., Yoneshima, Y., Otsubo, K., Tanaka, K., Nakanishi, Y. & Okamoto, I., 12月 2018, In: Lung Cancer. 126, p. 156-161 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Glucuronosyltransferase 1A1 100%
  • Glucuronosyltransferase 100%
  • Etoposide 72%
  • Allele 63%
  • Small Cell Lung Cancer 54%
  3 被引用数 (Scopus)

• Association of preoperative serum CRP with PD-L1 expression in 508 patients with non-small cell lung cancer: A comprehensive analysis of systemic inflammatory markers

  Akamine, T., Takada, K., Toyokawa, G., Kinoshita, F., Matsubara, T., Kozuma, Y., Haratake, N., Takamori, S., Hirai, F., Tagawa, T., Okamoto, T., Yoneshima, Y., Okamoto, I., Shimokawa, M., Oda, Y., Nakanishi, Y. & Maehara, Y., 3月 2018, In: Surgical Oncology. 27, 1, p. 88-94 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Programmed Death 1 Ligand 1 100%
  • C Reactive Protein 57%
  • C-Reactive Protein 57%
  • Marker 42%
  • Association 35%
  34 被引用数 (Scopus)

• Clinical significance of PD-L1 expression in brain metastases from non-small cell lung cancer

  Takamori, S., Toyokawa, G., Okamoto, I., Takada, K., Kinoshita, F., Kozuma, Y., Matsubara, T., Haratake, N., Akamine, T., Mukae, N., Hirai, F., Tagawa, T., Oda, Y., Iwaki, T., Iihara, K., Nakanishi, Y. & Maehara, Y., 1月 2018, In: Anticancer research. 38, 1, p. 553-557 5 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Programmed Cell Death 100%
  • Ligand 100%
  • Brain Metastasis 90%
  • Non Small Cell Lung Cancer 36%
  • Patient 18%
  26 被引用数 (Scopus)

• Detection of identical T cell clones in peritumoral pleural effusion and pneumonitis lesions in a cancer patient during immune-checkpoint blockade

  Tanaka, K., Yanagihara, T., Ikematsu, Y., Inoue, H., Ota, K., Kashiwagi, E., Suzuki, K., Hamada, N., Takeuchi, A., Tatsugami, K., Eto, M., Ijichi, K., Oda, Y., Otsubo, K., Yoneshima, Y., Iwama, E., Nakanishi, Y. & Okamoto, I., 7月 17 2018, In: Oncotarget. 9, 55, p. 30587-30593 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Immunity 100%
  • Bronchoalveolar Lavage Fluid 100%
  • T Cell Receptor 75%
  • Clone 75%
  • Lymphocyte 75%
  19 被引用数 (Scopus)

• Development of leptomeningeal carcinomatosis during a marked response of brain metastases to pembrolizumab in a patient with non-small-cell lung cancer

  Otsubo, K., Seki, N., Nakanishi, Y. & Okamoto, I., 3月 1 2018, In: Annals of Oncology. 29, 3, p. 780-781 2 p.

  研究成果: ジャーナルへの寄稿 › レター › 査読

  Open Access
  4 被引用数 (Scopus)

• Durable response to nivolumab in a lung adenocarcinoma patient with idiopathic pulmonary fibrosis

  Ide, M., Tanaka, K., Sunami, S., Asoh, T., Maeyama, T., Tsuruta, N., Nakanishi, Y. & Okamoto, I., 11月 2018, In: Thoracic Cancer. 9, 11, p. 1519-1521 3 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Idiopathic Pulmonary Fibrosis 100%
  • Patient 60%
  • Nivolumab 60%
  • Non Small Cell Lung Cancer 40%
  • Lung Adenocarcinoma 40%
  17 被引用数 (Scopus)

• Exploration of resistance mechanisms for epidermal growth factor receptor-tyrosine kinase inhibitors based on plasma analysis by digital polymerase chain reaction and next-generation sequencing

  Iwama, E., Sakai, K., Azuma, K., Harada, D., Nosaki, K., Hotta, K., Nishio, M., Kurata, T., Fukuhara, T., Akamatsu, H., Goto, K., Shimose, T., Kishimoto, J., Nakanishi, Y., Nishio, K. & Okamoto, I., 12月 2018, In: Cancer Science. 109, 12, p. 3921-3933 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Mutation 100%
  • Sample 71%
  • Epidermal Growth Factor Receptor 71%
  • Epidermal Growth Factor 71%
  • Next Generation Sequencing 57%
  21 被引用数 (Scopus)

• Expression of brain-derived neurotrophic factor and its receptor TrkB is associated with poor prognosis and a malignant phenotype in small cell lung cancer

  Kimura, S., Harada, T., Ijichi, K., Tanaka, K., Liu, R., Shibahara, D., Kawano, Y., Otsubo, K., Yoneshima, Y., Iwama, E., Nakanishi, Y. & Okamoto, I., 6月 2018, In: Lung Cancer. 120, p. 98-107 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Brain Derived Neurotrophic Factor 100%
  • Brain-Derived Neurotrophic Factor 100%
  • Small Cell Lung Cancer 78%
  • Cells 35%
  • Patient 28%
  20 被引用数 (Scopus)