分子生命科学系部門

研究成果

年別の研究成果 1982 2008 2009 2010 2012 2013 2016 2017 2018 2021 2024

• 95 学術誌
• 13 総説
• 4 コメント/討論
• 2 章
• 1 その他
  • 1 会議への寄与

年別の研究成果

年別の研究成果

検索結果

• 2024

  Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression

  Takahashi, F., Baba, T., Christianto, A., Yanai, S., Lee-Okada, H. C., Ishiwata, K., Nakabayashi, K., Hata, K., Ishii, T., Hasegawa, T., Yokomizo, T., Choi, M. H. & Morohashi, K.-I., 2月 27 2024, In: Cell Reports. 43, 2, 113715.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Gene Repression 100%
  • Sex Differentiation 50%
  • Glucocorticoid Receptor 25%
  3 被引用数 (Scopus)
• 2022

  Intrauterine Hyponutrition Reduces Fetal Testosterone Production and Postnatal Sperm Count in the Mouse

  Fujisawa, Y., Ono, H., Konno, A., Yao, I., Itoh, H., Baba, T., Morohashi, K., Katoh-Fukui, Y., Miyado, M., Fukami, M. & Ogata, T., 4月 1 2022, In: Journal of the Endocrine Society. 6, 4, bvac022.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Female 100%
  • Testosterone 100%
  • Sperm 100%
  • Mouse 100%
  • Fetus 50%
  1 被引用数 (Scopus)

• Prostaglandin E₂ receptor Ptger4b regulates female-specific peptidergic neurons and female sexual receptivity in medaka

  Fleming, T., Kikuchi, Y., Nakajo, M., Tachizawa, M., Inazumi, T., Tsuchiya, S., Sugimoto, Y., Saito, D., Suyama, M., Ohkawa, Y., Baba, T., Morohashi, K. I. & Okubo, K., 12月 2022, In: Communications Biology. 5, 1, 1215.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Neuron 100%
  • Peptidergic 71%
  • Oryzias 42%
  • Neuropeptide 42%
  • Estrogens 42%
  3 被引用数 (Scopus)

• Tmsb10 triggers fetal Leydig differentiation by suppressing the RAS/ERK pathway

  Inoue, M., Baba, T., Takahashi, F., Terao, M., Yanai, S., Shima, Y., Saito, D., Sugihara, K., Miura, T., Takada, S., Suyama, M., Ohkawa, Y. & Morohashi, K. I., 12月 2022, In: Communications Biology. 5, 1, 974.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Leydig Cell 100%
  • Cells 50%
  • Cell Differentiation 50%
  • Cellular Differentiation 50%
  • Differentiation 33%
  1 被引用数 (Scopus)
• 2021

  Eicosapentaenoic acid changes muscle transcriptome and intervenes in aging-related fiber type transition in male mice

  Yamazaki, H., Nishimura, M., Uehara, M., Kuribara-Souta, A., Yamamoto, M., Yoshikawa, N., Morohashi, K. I. & Tanaka, H., 2月 2021, In: American Journal of Physiology - Endocrinology and Metabolism. 320, 2, p. E346-E358

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Icosapentaenoic Acid 100%
  • Eicosapentaenoic Acid 100%
  • Mouse 47%
  • Aging 41%
  • Muscle 35%
  7 被引用数 (Scopus)

• GC-MS-based metabolic signatures reveal comparative steroidogenic pathways between fetal and adult mouse testes

  Han, S., Baba, T., Yanai, S., Byun, D. J., Morohashi, K. I., Kim, J. H. & Choi, M. H., 1月 2021, In: Andrology. 9, 1, p. 400-406 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Testes 100%
  • Steroid 77%
  • Adult 55%
  • Mouse 55%
  • Gas Chromatography Mass Spectrometry 44%
  7 被引用数 (Scopus)

• Gene expression and functional abnormalities in XX/Sry Leydig cells

  Yanai, S., Baba, T., Inui, K., Miyabayashi, K., Han, S., Inoue, M., Takahashi, F., Kanai, Y., Ohkawa, Y., Choi, M. H. & Morohashi, K. I., 12月 2021, In: Scientific reports. 11, 1, 719.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Karyotype 46,XX 100%
  • Interstitial Cell 63%
  • Leydig Cell 63%
  • Adult 45%
  • Sertoli Cell 27%
  4 被引用数 (Scopus)

• Generation of ovarian follicles from mouse pluripotent stem cells

  Yoshino, T., Suzuki, T., Nagamatsu, G., Yabukami, H., Ikegaya, M., Kishima, M., Kita, H., Imamura, T., Nakashima, K., Nishinakamura, R., Tachibana, M., Inoue, M., Shima, Y., Morohashi, K. I. & Hayashi, K., 7月 16 2021, In: Science. 373, 6552, eabe0237.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Cells 100%
  • Oocyte 83%
  • Somatics 33%
  • Culture 33%
  • Meiosis 33%
  89 被引用数 (Scopus)

• p97 and p47 function in membrane tethering in cooperation with FTCD during mitotic Golgi reassembly

  Kaneko, Y., Shimoda, K., Ayala, R., Goto, Y., Panico, S., Zhang, X. & Kondo, H., 5月 3 2021, In: EMBO Journal. 40, 9, e105853.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • P97 100%
  • Formiminotransferase Cyclodeaminase 100%
  • Membrane Fusion 25%
  • Mitochondrion 16%
  • Mitosis 16%
  11 被引用数 (Scopus)

• Sex differences in metabolic pathways are regulated by Pfkfb3 and Pdk4 expression in rodent muscle

  Christianto, A., Baba, T., Takahashi, F., Inui, K., Inoue, M., Suyama, M., Ono, Y., Ohkawa, Y. & Morohashi, K. I., 12月 2021, In: Communications Biology. 4, 1, 1264.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Metabolic Pathway 100%
  • Skeletal Muscle 100%
  • Pyruvate Dehydrogenase Kinase 100%
  • Nested Gene 66%
  • Transcriptome 66%
  9 被引用数 (Scopus)

• VCAM1-α4β1 integrin interaction mediates interstitial tissue reconstruction in 3-D re-aggregate culture of dissociated prepubertal mouse testicular cells

  Abe, K., Kon, S., Kameyama, H., Zhang, J. D., Morohashi, K. I., Shimamura, K. & Abe, S. I., 12月 2021, In: Scientific reports. 11, 1, 18332.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Cells 100%
  • Integrin 70%
  • Interstitial Cell 50%
  • Tissues 40%
  • Culture 40%
  6 被引用数 (Scopus)
• 2019

  Mouse polycomb group gene Cbx2 promotes osteoblastic but suppresses adipogenic differentiation in postnatal long bones

  Katoh-Fukui, Y., Baba, T., Sato, T., Otake, H., Nagakui-Noguchi, Y., Shindo, M., Suyama, M., Ohkawa, Y., Tsumura, H., Morohashi, K. I. & Fukami, M., 3月 2019, In: Bone. 120, p. 219-231 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Gene 100%
  • Differentiation 66%
  • Cell Lineage 33%
  • Mesenchymal Stem Cell 33%
  • Bone Growth 33%
  10 被引用数 (Scopus)

• Three populations of adult Leydig cells in mouse testes revealed by a novel mouse HSD3B1-specific rat monoclonal antibody

  Yokoyama, C., Chigi, Y., Baba, T., Ohshitanai, A., Harada, Y., Takahashi, F. & Morohashi, K. I., 4月 16 2019, In: Biochemical and Biophysical Research Communications. 511, 4, p. 916-920 5 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Interstitial Cell 100%
  • Leydig Cell 100%
  • Adult 50%
  • Mouse 28%
  • Monoclonal Antibody 21%
  18 被引用数 (Scopus)
• 2018

  Ad4BP/SF-1 regulates cholesterol synthesis to boost the production of steroids

  Baba, T., Otake, H., Inoue, M., Sato, T., Ishihara, Y., Moon, J. Y., Tsuchiya, M., Miyabayashi, K., Ogawa, H., Shima, Y., Wang, L., Sato, R., Yamazaki, T., Suyama, M., Nomura, M., Choi, M. H., Ohkawa, Y. & Morohashi, K. I., 12月 1 2018, In: Communications Biology. 1, 1, 18.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Metabolic Pathway 100%
  • Nested Gene 60%
  • Steroid 40%
  • Cholesterol 20%
  • Glycolysis 20%
  22 被引用数 (Scopus)

• Adrenocortical development: Lessons from mouse models

  Dumontet, T., Sahut-Barnola, I., Septier, A., Montanier, N., Plotton, I., Roucher-Boulez, F., Ducros, V., Lefrançois-Martinez, A. M., Pointud, J. C., Zubair, M., Morohashi, K. I., Breault, D. T., Val, P. & Martinez, A., 6月 2018, In: Annales d'Endocrinologie. 79, 3, p. 95-97 3 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Cyclic AMP Dependent Protein Kinase 100%
  • Zona Reticularis 100%
  • Protein Kinase A 100%
  • Adult 50%
  • Androgen 50%
  8 被引用数 (Scopus)

• PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal

  Dumontet, T., Sahut-Barnola, I., Septier, A., Montanier, N., Plotton, I., Roucher-Boulez, F., Ducros, V., Lefrançois-Martinez, A. M., Pointud, J. C., Zubair, M., Morohashi, K. I., Breault, D. T., Val, P. & Martinez, A., 1月 25 2018, In: JCI Insight. 3, 2

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Cells 100%
  • Adult 100%
  • Differentiation 100%
  • Drive 100%
  • Adrenal Cortex 100%
  75 被引用数 (Scopus)

• The role of Ad4BP/SF-1 in the development of adrenal gland and the synthesis of adrenal steroid

  Baba, T., 2018, In: Japanese Journal of Clinical Urology. 72, 6, p. 424-429 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読
• 2017

  Alterations in Fetal Leydig Cell Gene Expression during Fetal and Adult Development

  Miyabayashi, K., Shima, Y., Inoue, M., Sato, T., Baba, T., Ohkawa, Y., Suyama, M. & Morohashi, K. I., 5月 1 2017, In: Sexual Development. 11, 2, p. 53-63 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Interstitial Cell 100%
  • Leydig Cell 100%
  • Adult 54%
  • Testes 45%
  • Gene Expression 18%
  28 被引用数 (Scopus)

• Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells

  Shishido, Y., Baba, T., Sato, T., Shima, Y., Miyabayashi, K., Inoue, M., Akiyama, H., Kimura, H., Kanai, Y., Ishihara, Y., Haraguchi, S., Miyazaki, A., Rozman, D., Yamazaki, T., Choi, M. H., Ohkawa, Y., Suyama, M. & Morohashi, K. I., 2017, In: Scientific reports. 7, 41912.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Karyotype 46,XX 100%
  • Sertoli Cell 87%
  • Germ Cell 37%
  • Lactic Acid 37%
  • Demethylase 25%
  3 被引用数 (Scopus)

• Identical NR5A1 Missense Mutations in Two Unrelated 46,XX Individuals with Testicular Tissues

  Igarashi, M., Takasawa, K., Hakoda, A., Kanno, J., Takada, S., Miyado, M., Baba, T., Morohashi, K. I., Tajima, T., Hata, K., Nakabayashi, K., Matsubara, Y., Sekido, R., Ogata, T., Kashimada, K. & Fukami, M., 1月 1 2017, In: Human mutation. 38, 1, p. 39-42 4 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Mutation 100%
  • Karyotype 46,XX 83%
  • Patient 33%
  • Testis Development 33%
  • Disorders of Sex Development 33%
  45 被引用数 (Scopus)

• Leydig progenitor cells in fetal testis

  Shima, Y. & Morohashi, K. I., 4月 15 2017, In: Molecular and Cellular Endocrinology. 445, p. 55-64 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Interstitial Cell 100%
  • Adult 35%
  • Testes 29%
  • Androgen 11%
  • Cell Population 11%
  38 被引用数 (Scopus)

• Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth

  Syu, J. S., Baba, T., Huang, J. Y., Ogawa, H., Hsieh, C. H., Hu, J. X., Chen, T. Y., Lin, T. C., Tsuchiya, M., Morohashi, K. I., Huang, B. M., Lu, F. I. & Wang, C. Y., 2017, In: Scientific reports. 7, 1, 240.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Steroidogenic Factor 1 100%
  • Cell Growth 58%
  • S Phase 16%
  • Autophagy 16%
  • Cyclin E1 16%
  13 被引用数 (Scopus)

• Mechanism for sex differentiation of the gonads

  Morohashi, K. I., 2017, In: Japanese Journal of Clinical Urology. 71, 10, p. 746-751 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

• Role of Ad4-binding protein/steroidogenic factor 1 in regulating NADPH production in adrenocortical Y-1 cells

  Li, B., Baba, T., Miyabayashi, K., Sato, T., Shima, Y., Ichinose, T., Miura, D., Ohkawa, Y., Suyama, M. & Morohashi, K. I., 2017, In: Endocrine Journal. 64, 3, p. 315-324 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Nicotinamide Adenine Dinucleotide Phosphate 100%
  • Binding Protein 81%
  • Steroidogenic Factor 1 81%
  • Nested Gene 63%
  • Species 18%
  9 被引用数 (Scopus)

• Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1

  Xing, Y., Morohashi, K. I., Ingraham, H. A. & Hammer, G. D., 10月 15 2017, In: Development (Cambridge). 144, 20, p. 3798-3807 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Enhancer Region 100%
  • Sumoylation 83%
  • Nested Gene 16%
  • Development 16%
  • DNA Binding 16%
  19 被引用数 (Scopus)
• 2016

  Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling

  Otera, H., Miyata, N., Kuge, O. & Mihara, K., 2016, In: Journal of Cell Biology. 212, 5, p. 531-544 14 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Crista 100%
  • Cytochrome C 66%
  • Mitochondrial Fission 50%
  • Intrinsic Apoptosis 33%
  • Eicosanoid Receptor 33%
  183 被引用数 (Scopus)

• Isolation and characterization of Fetal Leydig progenitor cells of male mice

  Inoue, M., Shima, Y., Miyabayashi, K., Tokunaga, K., Sato, T., Baba, T., Ohkawa, Y., Akiyama, H., Suyama, M. & Morohashi, K. I., 3月 2016, In: Endocrinology. 157, 3, p. 1222-1233 12 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Interstitial Cell 100%
  • Enhanced Green Fluorescent Protein 83%
  • Cells 50%
  • Stem Cell 50%
  • Gene 33%
  40 被引用数 (Scopus)

• Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy

  Yamashita, S. I., Jin, X., Furukawa, K., Hamasaki, M., Nezu, A., Otera, H., Saigusa, T., Yoshimori, T., Sakai, Y., Mihara, K. & Kanki, T., 2016, In: Journal of Cell Biology. 215, 5, p. 649-665 17 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Mitophagy 100%
  • Autophagosome 75%
  • Mitochondrion 50%
  • Mitochondria 50%
  • Membrane 25%
  150 被引用数 (Scopus)

• Neuregulin 1 regulates proliferation of leydig cells to support spermatogenesis and sexual behavior in adult mice

  Umehara, T., Kawashima, I., Kawai, T., Hoshino, Y., Morohashi, K. I., Shima, Y., Zeng, W., Richards, J. S. & Shimada, M., 12月 2016, In: Endocrinology. 157, 12, p. 4899-4913 15 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Interstitial Cell 100%
  • Adult 66%
  • Testes 66%
  • Mutant 55%
  • Infant 55%
  17 被引用数 (Scopus)

• SF-1 deficiency causes lipid accumulation in Leydig cells via suppression of STAR and CYP11A1

  Hatano, M., Migita, T., Ohishi, T., Shima, Y., Ogawa, Y., Morohashi, K.-I., Hasegawa, Y. & Shibasaki, F., 11月 1 2016, In: Endocrine. 54, 2, p. 484-496 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Steroidogenic Factor 1 100%
  • Lipid Storage 60%
  • Leydig Cell 50%
  • Protein 40%
  • Cholesterol 30%
  36 被引用数 (Scopus)
• 2015

  Fetal leydig cells persist as an androgen-independent subpopulation in the postnatal testis

  Shima, Y., Matsuzaki, S., Miyabayashi, K., Otake, H., Baba, T., Kato, S., Huhtaniemi, I. & Morohashi, K.-I., 11月 2015, In: Molecular Endocrinology. 29, 11, p. 1581-1593 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Interstitial Cell 100%
  • Leydig Cell 100%
  • Mouse 40%
  • Adult 30%
  • Androgen Receptor 20%
  59 被引用数 (Scopus)

• Heterogeneity of ovarian theca and interstitial gland cells in Mice

  Miyabayashi, K., Tokunaga, K., Otake, H., Baba, T., Shima, Y. & Morohashi, K., 6月 3 2015, In: PloS one. 10, 6, e0128352.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Cells 100%
  • Reporter Gene 66%
  • Gene Expression 50%
  • Gland 50%
  • Ovary 50%
  19 被引用数 (Scopus)

• Selective autophagic receptor p62 regulates the abundance of transcriptional coregulator ARIP4 during nutrient starvation

  Tsuchiya, M., Isogai, S., Taniguchi, H., Tochio, H., Shirakawa, M., Morohashi, K. I., Hiraoka, Y., Haraguchi, T. & Ogawa, H., 9月 28 2015, In: Scientific reports. 5, 14498.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Protein 100%
  • Androgen Receptor 72%
  • Ubiquitin 36%
  • Nuclear Receptor 18%
  • Regulatory Mechanism 18%
  9 被引用数 (Scopus)

• Testicular dysgenesis/regression without campomelic dysplasia in patients carrying missense mutations and upstream deletion of sox9

  Katoh-Fukui, Y., Igarashi, M., Nagasaki, K., Horikawa, R., Nagai, T., Tsuchiya, T., Suzuki, E., Miyado, M., Hata, K., Nakabayashi, K., Hayashi, K., Matsubara, Y., Baba, T., Morohashi, K. I., Igarashi, A., Ogata, T., Takada, S. & Fukami, M., 11月 2015, In: Molecular Genetics and Genomic Medicine. 3, 6, p. 550-557 8 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • SOX9 100%
  • Patient 85%
  • Dysplasia 57%
  • Mutation 42%
  • Nested Gene 28%
  17 被引用数 (Scopus)
• 2014

  Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1

  Baba, T., Otake, H., Sato, T., Miyabayashi, K., Shishido, Y., Wang, C. Y., Shima, Y., Kimura, H., Yagi, M., Ishihara, Y., Hino, S., Ogawa, H., Nakao, M., Yamazaki, T., Kang, D., Ohkawa, Y., Suyama, M., Chung, B. C. & Morohashi, K. I., 4月 14 2014, In: Nature communications. 5, 3634.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Nested Gene 100%
  • Gene 100%
  • Genes 100%
  • Nuclear Receptor 50%
  • Tissues 50%
  58 被引用数 (Scopus)

• Identification of myelin transcription factor 1 (MyT1) as a subunit of the neural cell type-specific lysine-specific demethylase 1 (LSD1) complex

  Yokoyama, A., Igarashi, K., Sato, T., Takagi, K., Otsuka, M. I., Shishido, Y., Baba, T., Ito, R., Kanno, J., Ohkawa, Y., Morohashi, K. I. & Sugawara, A., 6月 27 2014, In: Journal of Biological Chemistry. 289, 26, p. 18152-18162 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Lysine 100%
  • Demethylase 100%
  • Transcription Factors 80%
  • Myelin 80%
  • Fibrinogen 80%
  33 被引用数 (Scopus)

• Influenza a virus protein PB1-F2 translocates into mitochondria via Tom40 channels and impairs innate immunity

  Yoshizumi, T., Ichinohe, T., Sasaki, O., Otera, H., Kawabata, S. I., Mihara, K. & Koshiba, T., 8月 20 2014, In: Nature communications. 5, 4713.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Innate Immune System 100%
  • Mitochondrion 60%
  • Influenza 40%
  • Inner Membrane 40%
  • Signal Transduction 20%
  177 被引用数 (Scopus)
• 2013

  Aristaless Related Homeobox Gene, Arx, Is Implicated in Mouse Fetal Leydig Cell Differentiation Possibly through Expressing in the Progenitor Cells

  Miyabayashi, K., Katoh-Fukui, Y., Ogawa, H., Baba, T., Shima, Y., Sugiyama, N., Kitamura, K. & Morohashi, K. I., 6月 28 2013, In: PloS one. 8, 6, e68050.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Interstitial Cell 100%
  • Testes 45%
  • Cells 36%
  • Stem Cell 36%
  • Cell Differentiation 27%
  57 被引用数 (Scopus)

• Contribution of Leydig and Sertoli cells to testosterone production in mouse fetal testes

  Shima, Y., Miyabayashi, K., Haraguchi, S., Arakawa, T., Otake, H., Baba, T., Matsuzaki, S., Shishido, Y., Akiyama, H., Tachibana, T., Tsutsui, K. & Morohashi, K.-I., 2013, In: Molecular Endocrinology. 27, 1, p. 63-73 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Interstitial Cell 100%
  • Testosterone 53%
  • Adult 30%
  • Testes 30%
  • Sertoli Cell 30%
  176 被引用数 (Scopus)

• Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphology

  Onoue, K., Jofuku, A., Ban-Ishihara, R., Ishihara, T., Maeda, M., Koshiba, T., Itoh, T., Fukuda, M., Otera, H., Oka, T., Takano, H., Mizushima, N., Mihara, K. & Ishihara, N., 1月 1 2013, In: Journal of cell science. 126, 1, p. 176-185 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Morphology 100%
  • Regulatory Mechanism 66%
  • Mitochondrial Fission 66%
  • Protein 33%
  • Binding Protein 33%
  115 被引用数 (Scopus)

• Heterogeneity in sexual bipotentiality and plasticity of granulosa cells in developing mouse ovaries

  Harikae, K., Miura, K., Shinomura, M., Matoba, S., Hiramatsu, R., Tsunekawa, N., Kanai-Azuma, M., Kurohmaru, M., Morohashi, K. I. & Kanai, Y., 7月 2013, In: Journal of cell science. 126, 13, p. 2834-2844 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • SOX9 100%
  • Mouse 50%
  • Plasticity 33%
  • Folliculogenesis 33%
  • Aptitude 16%
  29 被引用数 (Scopus)

• Homeoproteins Six1 and Six4 regulate male sex determination and mouse gonadal development

  Fujimoto, Y., Tanaka, S. S., Yamaguchi, Y. L., Kobayashi, H., Kuroki, S., Tachibana, M., Shinomura, M., Kanai, Y., Morohashi, K. I., Kawakami, K. & Nishinakamura, R., 8月 26 2013, In: Developmental Cell. 26, 4, p. 416-430 15 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Gonad Development 100%
  • Precursor 75%
  • Mutant 75%
  • Regulatory Mechanism 50%
  • Growth 25%
  74 被引用数 (Scopus)

• Mitotic phosphorylation of VCIP135 blocks p97ATPase-mediated Golgi membrane fusion

  Totsukawa, G., Matsuo, A., Kubota, A., Taguchi, Y. & Kondo, H., 4月 2013, In: Biochemical and Biophysical Research Communications. 433, 2, p. 237-242 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • P97 100%
  • Membrane Fusion 87%
  • Phosphorylation 75%
  • Serine 62%
  • Mitosis 50%
  19 被引用数 (Scopus)
• 2012

  Cbx2, a polycomb group gene, is required for Sry gene expression in mice

  Katoh-Fukui, Y., Miyabayashi, K., Komatsu, T., Owaki, A., Baba, T., Shima, Y., Kidokoro, T., Kanai, Y., Schedl, A., Wilhelm, D., Koopman, P., Okuno, Y. & Morohashi, K. I., 2月 2012, In: Endocrinology. 153, 2, p. 913-924 12 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Gene 100%
  • Testes 100%
  • Gonad 100%
  • Nested Gene 100%
  • Mouse 100%
  120 被引用数 (Scopus)

• Identification of an enhancer in the Ad4BP/SF-1 gene specific for fetal leydig cells

  Shima, Y., Miyabayashi, K., Baba, T., Otake, H., Oka, S., Zubair, M. & Morohashi, K. I., 1月 2012, In: Endocrinology. 153, 1, p. 417-425 9 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Steroidogenic Factor 1 100%
  • Enhancer Region 50%
  • Interstitial Cell 31%
  • Leydig Cell 31%
  • Gene 25%
  48 被引用数 (Scopus)

• Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal leydig cells but permits normal genital and reproductive development

  Miyado, M., Nakamura, M., Miyado, K., Morohashi, K. I., Sano, S., Nagata, E., Fukami, M. & Ogata, T., 12月 1 2012, In: Endocrinology. 153, 12, p. 6033-6040 8 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Gene 100%
  • Messenger RNA 100%
  • Interstitial Cell 100%
  • Male 80%
  • Development 60%
  26 被引用数 (Scopus)

• Pex5p imports folded tetrameric catalase by interaction with pex13p

  Otera, H. & Fujiki, Y., 10月 2012, In: Traffic. 13, 10, p. 1364-1377 14 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Catalase 100%
  • Peroxisomal Targeting Signal 62%
  • Peroxisome 37%
  • Protein 25%
  • Mutant 25%
  30 被引用数 (Scopus)

• Wnt family genes and their modulation in the ovary-independent and persistent vaginal epithelial cell proliferation and keratinization induced by neonatal diethylstilbestrol exposure in mice

  Nakamura, T., Miyagawa, S., Katsu, Y., Watanabe, H., Mizutani, T., Sato, T., Morohashi, K. I., Takeuchi, T., Iguchi, T. & Ohta, Y., 6月 14 2012, In: Toxicology. 296, 1-3, p. 13-19 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Vagina 100%
  • Diethylstilbestrol 100%
  • Epithelial Cell 80%
  • Cell Proliferation 40%
  • Keratinization 40%
  20 被引用数 (Scopus)
• 2011

  Discovery of the membrane receptor for mitochondrial fission GTPase Drp1

  Otera, H. & Mihara, K., 2011, In: Small GTPases. 2, 3, p. 167-172 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Mitochondrial Fission 100%
  • Yeast 80%
  • Membrane 60%
  • Mammal 40%
  • Mitochondrion 40%
  58 被引用数 (Scopus)

• DNA methylation of intronic enhancers directs tissue-specific expression of steroidogenic factor 1/adrenal 4 binding protein (SF-1/Ad4BP)

  Hoivik, E. A., Bjanesoy, T. E., Mai, O., Okamoto, S., Minokoshi, Y., Shima, Y., Morohashi, K. I., Boehm, U. & Bakke, M., 5月 2011, In: Endocrinology. 152, 5, p. 2100-2112 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Steroidogenic Factor 1 100%
  • Enhancer Region 66%
  • Growth Hormone Treatment 41%
  • DNA Methylation 33%
  • Promoter Region 25%
  50 被引用数 (Scopus)