先端分子・細胞治療科

研究成果

年別の研究成果 1997 2008 2014 2015 2016 2018 2022 2022

• 56 学術誌
• 2 コメント/討論
• 2 総説
• 1 章

年別の研究成果

年別の研究成果

検索結果

• 2022

  C11orf21, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO

  Matsumoto, A., Yoshida, T., Shima, T., Yamasaki, K., Tadagaki, K., Kondo, N., Kuwahara, Y., Zhang, D. E. & Okuda, T., 1月 2022, In: BBA Advances. 2, 100047.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • RUNX1 100%
  • Myeloid 29%
  • Nested Gene 17%
  • Luciferase 11%
  • Computer Model 11%
  1 被引用数 (Scopus)

• Incidence of refractory cytomegalovirus infection after allogeneic hematopoietic stem cell transplantation

  Jinnouchi, F., Mori, Y., Yoshimoto, G., Yamauchi, T., Nunomura, T., Yurino, A., Hayashi, M., Yuda, J., Shima, T., Odawara, J., Takashima, S., Kamezaki, K., Kato, K., Miyamoto, T., Akashi, K. & Takenaka, K., 1月 2022, In: International journal of hematology. 115, 1, p. 96-106 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Cytomegalovirus 100%
  • Cytomegalovirus Infection 80%
  • Incidence 40%
  • Transplantation 40%
  • Mutation 40%

• Prognostic value of pre-transplantation total metabolic tumor volume on ¹⁸fluoro-2-deoxy-d-glucose positron emission tomography–computed tomography in relapsed and refractory aggressive lymphoma

  Sugio, T., Baba, S., Mori, Y., Yoshimoto, G., Kamesaki, K., Takashima, S., Urata, S., Shima, T., Miyawaki, K., Kikushige, Y., Kunisaki, Y., Numata, A., Takenaka, K., Iawasaki, H., Miyamoto, T., Ishigami, K., Akashi, K. & Kato, K., 2022, (印刷中) In: International journal of hematology.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Neoplasm 100%
  • Patient 71%
  • Prognosis 57%
  • Autologous Hematopoietic Stem Cell Transplantation 57%
  • Allogeneic Hematopoietic Stem Cell Transplantation 57%

• Prospective study of adoptive activated αβT lymphocyte immunotherapy for refractory cancers: development and validation of a response scoring system

  Nonami, A., Matsuo, R., Funakoshi, K., Nakayama, T., Goto, S., Iino, T., Takaishi, S., Mizuno, S., Akashi, K. & Eto, M., 2022, (印刷中) In: Cytotherapy.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Patient 100%
  • T Lymphocyte 100%
  • Scoring System 100%
  • Combination Therapy 75%
  • Prognostic Factor 75%

• Risk factors for late cytomegalovirus infection after completing letermovir prophylaxis

  Mori, Y., Harada, T., Yoshimoto, G., Shima, T., Numata, A., Jinnouchi, F., Yamauchi, T., Kikushige, Y., Kunisaki, Y., Kato, K., Takenaka, K., Akashi, K. & Miyamoto, T., 2022, (印刷中) In: International journal of hematology.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Cytomegalovirus Infection 100%
  • Transplantation 44%
  • Cell Transplantation 33%
  • Incidence 22%
  • Time 11%
  5 被引用数 (Scopus)
• 2021

  Individual HLAs influence immunological events in allogeneic stem cell transplantation from HLA-identical sibling donors

  on behalf of the HLA Working Group of the Japan Society for Hematopoietic Cell Transplantation, 3月 2021, In: Bone Marrow Transplantation. 56, 3, p. 646-654 9 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Human Leukocyte Antigen 100%
  • Acute Graft Versus Host Disease 44%
  • Transplantation 33%
  • Contrast 11%
  • Biological Product 11%

• Platelet decrease and efficacy of platelet-rich plasma return following peripheral blood stem cell apheresis

  Shima, T., Sakoda, T., Henzan, T., Kunisaki, Y., Sugio, T., Kamezaki, K., Iwasaki, H., Teshima, T., Maeda, T., Akashi, K. & Miyamoto, T., 10月 2021, In: Journal of Clinical Apheresis. 36, 5, p. 687-696 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Platelet 100%
  • Peripheral Blood Stem Cell 61%
  • Apheresis 53%
  • Thrombocyte Rich Plasma 46%
  • Patient 7%
• 2020

  A case of a patient receiving combination therapy with paclitaxel plus bevacizumab and adoptive activated αβ T-cell immunotherapy in advanced breast cancer

  Masuda, T., Nonami, A., Tanaka, F., Ando, Y., Eto, M. & Mimori, K., 12月 2020, In: Breast Journal. 26, 12, p. 2420-2423 4 p.

  研究成果: ジャーナルへの寄稿 › コメント/討論 › 査読

  Open Access
• 2019

  Periodontitis Is Associated with Chronic Obstructive Pulmonary Disease

  Takeuchi, K., Matsumoto, K., Furuta, M., Fukuyama, S., Takeshita, T., Ogata, H., Suma, S., Shibata, Y., Shimazaki, Y., Hata, J., Ninomiya, T., Nakanishi, Y., Inoue, H. & Yamashita, Y., 5月 1 2019, In: Journal of Dental Research. 98, 5, p. 534-540 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Chronic Obstructive Lung Disease 100%
  • Periodontitis 91%
  • Confounder 8%
  • Cohort Study 8%
  46 被引用数 (Scopus)
• 2018

  A novel combination therapy for human oxaliplatin-resistant colorectal cancer using oxaliplatin and coxsackievirus A11

  Wang, B., Ogata, H., Takishima, Y., Miyamoto, S., Inoue, H., Kuroda, M., Yamada, K., Hijikata, Y., Murahashi, M., Shimizu, H., Okazaki, T., Nakanishi, Y. & Tani, K., 11月 2018, In: Anticancer research. 38, 11, p. 6121-6126 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Oxaliplatin 100%
  • Enterovirus 75%
  • Colorectal Cancer 66%
  • Therapeutic Procedure 33%
  • Cancer Cell 25%
  7 被引用数 (Scopus)

• A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors

  Hijikata, Y., Okazaki, T., Tanaka, Y., Murahashi, M., Yamada, Y., Yamada, K., Takahashi, A., Inoue, H., Kishimoto, J., Nakanishi, Y., Oda, Y., Nakamura, Y. & Tani, K., 1月 2018, In: PloS one. 13, 1, e0187878.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Protein 100%
  • Ring Finger 100%
  • Patient 83%
  • Inpatient 83%
  • Cyclophosphamide 83%
  12 被引用数 (Scopus)

• Comparative quantification of chemotherapy-induced nausea and emesis between the common terminology criteria for adverse events and the multinational association of supportive care in cancer antiemesis tool

  Uchida, M., Nakamura, T., Shima, T., Yoshimoto, G., Kato, K., Hosohata, K., Miyamoto, T. & Akashi, K., 2018, In: Biological and Pharmaceutical Bulletin. 41, 11, p. 1667-1671 5 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Adverse Event 100%
  • Patient 87%
  • Malignant Neoplasm 50%
  • Chemotherapy 50%
  • Association 37%
  4 被引用数 (Scopus)

• Gastrointestinal Graft-versus-Host Disease Is a Risk Factor for Postengraftment Bloodstream Infection in Allogeneic Hematopoietic Stem Cell Transplant Recipients

  Mori, Y., Yoshimoto, G., Nishida, R., Sugio, T., Miyawaki, K., Shima, T., Nagasaki, Y., Miyake, N., Harada, Y., Kunisaki, Y., Kamezaki, K., Numata, A., Kato, K., Shiratsuchi, M., Maeda, T., Takenaka, K., Iwasaki, H., Shimono, N., Akashi, K. & Miyamoto, T., 11月 2018, In: Biology of Blood and Marrow Transplantation. 24, 11, p. 2302-2309 8 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Bloodstream Infection 100%
  • Patient 42%
  • Hematopoietic Stem Cell 42%
  • Stem Cell Transplant 42%
  • Graft Versus Host Reaction 42%
  17 被引用数 (Scopus)

• Human Herpes Virus-6–Associated Encephalitis/Myelitis Mimicking Calcineurin Inhibitor–Induced Pain Syndrome in Allogeneic Stem Cell Transplantation Recipients

  Yoshimoto, G., Mori, Y., Kato, K., Shima, T., Miyawaki, K., Kikushige, Y., Kamezaki, K., Numata, A., Maeda, T., Takenaka, K., Iwasaki, H., Teshima, T., Akashi, K. & Miyamoto, T., 12月 2018, In: Biology of Blood and Marrow Transplantation. 24, 12, p. 2540-2548 9 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Herpes 100%
  • Calcineurin 75%
  • Myelitis 75%
  • Encephalitis 41%
  • DNA 25%
  5 被引用数 (Scopus)

• Identification of tumoricidal TCRs from tumor-infiltrating lymphocytes by single-cell analysis

  Shitaoka, K., Hamana, H., Kishi, H., Hayakawa, Y., Kobayashi, E., Sukegawa, K., Piao, X., Lyu, F., Nagata, T., Sugiyama, D., Nishikawa, H., Tanemura, A., Katayama, I., Murahashi, M., Takamatsu, Y., Tani, K., Ozawa, T. & Muraguchi, A., 4月 2018, In: Cancer Immunology Research. 6, 4, p. 378-388 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • T Cell Receptor 100%
  • T Lymphocyte Receptor 38%
  • Neoplasm 30%
  • Cells 23%
  • Analysis 15%
  25 被引用数 (Scopus)

• Investigator initiated clinical trial of cancer vaccine OCV-C01 in advanced and recurrent biliary tract cancer

  Murahashi, M., Ogata, H., Okazaki, T., Hijikata, Y., Yamada, K., Tsuruta, T., Kishimoto, J., Funakoshi, K., Todaka, K., Nakanishi, Y. & Tani, K., 10月 2018, In: Annals of oncology : official journal of the European Society for Medical Oncology. 29 Suppl 7, p. vii60

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

• RBPJ and MAML3: Potential therapeutic targets for small cell lung cancer

  Onishi, H., Ichimiya, S., Yanai, K., Umebayashi, M., Nakamura, K., Yamasaki, A., Imaizumi, A., Nagai, S., Murahashi, M., Ogata, H. & Morisaki, T., 8月 2018, In: Anticancer research. 38, 8, p. 4543-4547 5 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Combination Therapy 100%
  • Small Cell Lung Cancer 80%
  • Chemosensitivity 60%
  • Cells 20%
  • Development 20%
  13 被引用数 (Scopus)
• 2017

  Mobilization of human immature hematopoietic progenitors through combinatory use of bortezomib and immunomodulatory drugs

  Tochigi, T., Aoki, T., Kikushige, Y., Kamimura, T., Ito, Y., Shima, T., Yamauchi, T., Mori, Y., Yoshimoto, G., Kamezaki, K., Kato, K., Takenaka, K., Iwasaki, H., Akashi, K. & Miyamoto, T., 4月 1 2017, In: International journal of hematology. 105, 4, p. 423-432 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Immunomodulatory Drug 100%
  • Drug 100%
  • Bortezomib 100%
  • Cells 80%
  • Dexamethasone 60%
  2 被引用数 (Scopus)
• 2016

  A novel, polymer-coated oncolytic measles virus overcomes immune suppression and induces robust antitumor activity

  Nosaki, K., Hamada, K., Takashima, Y., Sagara, M., Matsumura, Y., Miyamoto, S., Hijikata, Y., Okazaki, T., Nakanishi, Y. & Tani, K., 11月 2 2016, In: Molecular Therapy - Oncolytics. 3, p. 16022 1 p., 16022.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Polymer 100%
  • Virus 83%
  • Antitumor Activity 66%
  • Malignant Neoplasm 50%
  • Mouse 50%
  30 被引用数 (Scopus)

• Ascites retention during mogamulizumab treatment in a patient with adult T-cell leukemia/lymphoma

  Shima, T., Kamezaki, K., Higashioka, K., Takashima, S., Yoshimoto, G., Kato, K., Muta, T., Takenaka, K., Iwasaki, H., Miyamoto, T. & Akashi, K., 2016, In: Internal Medicine. 55, 13, p. 1793-1796 4 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Ascites 100%
  • Mogamulizumab 83%
  • Adult T-Cell Leukemia/Lymphoma 50%
  • T Cell Leukemia 50%
  • Woman 16%
  2 被引用数 (Scopus)

• Mogamulizumab Treatment Prior to Allogeneic Hematopoietic Stem Cell Transplantation Induces Severe Acute Graft-versus-Host Disease

  Sugio, T., Kato, K., Aoki, T., Ohta, T., Saito, N., Yoshida, S., Kawano, I., Henzan, H., Kadowaki, M., Takase, K., Muta, T., Miyawaki, K., Yamauchi, T., Shima, T., Takashima, S., Mori, Y., Yoshimoto, G., Kamezaki, K., Takenaka, K., Iwasaki, H., & 6 othersOgawa, R., Ohno, Y., Eto, T., Kamimura, T., Miyamoto, T. & Akashi, K., 9月 1 2016, In: Biology of Blood and Marrow Transplantation. 22, 9, p. 1608-1614 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Mogamulizumab 100%
  • Allogeneic Hematopoietic Stem Cell Transplantation 66%
  • Adult 55%
  • Leukemia 55%
  • Graft Versus Host Reaction 55%
  42 被引用数 (Scopus)

• Phase I clinical trial of a five-peptide cancer vaccine combined with cyclophosphamide in advanced solid tumors

  Murahashi, M., Hijikata, Y., Yamada, K., Tanaka, Y., Kishimoto, J., Inoue, H., Marumoto, T., Takahashi, A., Okazaki, T., Takeda, K., Hirakawa, M., Fujii, H., Okano, S., Morita, M., Baba, E., Mizumoto, K., Maehara, Y., Tanaka, M., Akashi, K., Nakanishi, Y., & 5 othersYoshida, K., Tsunoda, T., Tamura, K., Nakamura, Y. & Tani, K., 5月 1 2016, In: Clinical Immunology. 166-167, p. 48-58 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Clinical Trial 100%
  • Peptide 75%
  • Cyclophosphamide 75%
  • Patient 50%
  • Immune Response 50%
  43 被引用数 (Scopus)
• 2015

  A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression

  Kikushige, Y., Miyamoto, T., Yuda, J., Jabbarzadeh-Tabrizi, S., Shima, T., Takayanagi, S. I., Niiro, H., Yurino, A., Miyawaki, K., Takenaka, K., Iwasaki, H. & Akashi, K., 9月 3 2015, In: Cell stem cell. 17, 3, p. 341-352 12 p., 1815.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Myeloid 100%
  • Ecalectin 85%
  • Galectin 85%
  • T Cell 71%
  • Immunoglobulin 71%
  175 被引用数 (Scopus)

• CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: Redefinition of murine common myeloid progenitor

  Miyawaki, K., Arinobu, Y., Iwasaki, H., Kohno, K., Tsuzuki, H., Iino, T., Shima, T., Kikushige, Y., Takenaka, K., Miyamoto, T. & Akashi, K., 3月 1 2015, In: STEM CELLS. 33, 3, p. 976-987 12 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Cells 100%
  • Hematopoiesis 100%
  • Transcription Factor GATA 1 100%
  • Gene Expression 50%
  • Adult 50%
  32 被引用数 (Scopus)

• Colitis mimicking graft-versus-host disease during treatment with the anti-CCR4 monoclonal antibody, mogamulizumab

  Ishitsuka, K., Murahashi, M., Katsuya, H., Mogi, A., Masaki, M., Kawai, C., Goto, T., Ishizu, M., Ikari, Y., Takamatsu, Y., Ishibashi, H., Nimura, S., Takeshita, M. & Tamura, K., 10月 1 2015, In: International journal of hematology. 102, 4, p. 493-497 5 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Mogamulizumab 100%
  • Monoclonal Antibody 50%
  • Graft Versus Host Reaction 50%
  • Chemokine Receptor 50%
  • Beta Chemokine 50%
  10 被引用数 (Scopus)

• Preserved in vivo reconstitution ability of PBSCs cryopreserved for a decade at -80 °c

  Shima, T., Iwasaki, H., Yamauchi, T., Kadowaki, M., Kiyosuke, M., Mochimaru, T., Takenaka, K., Miyamoto, T., Akashi, K. & Teshima, T., 9月 4 2015, In: Bone Marrow Transplantation. 50, 9, p. 1195-1200 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Rate 100%
  • Viability 100%
  • Cells 100%
  • Engraftment 100%
  • Electric Potential 100%
  10 被引用数 (Scopus)

• Successful treatment of adult Langerhans cell histiocytosis with intensified chemotherapy

  Minami, M., Shima, T., Kato, K., Yamamoto, H., Tsuchihashi, K., Oku, S., Shimokawa, T., Tochigi, T., Yoshimoto, G., Kamezaki, K., Takenaka, K., Iwasaki, H., Oda, Y., Miyamoto, T. & Akashi, K., 8月 11 2015, In: International journal of hematology. 102, 2, p. 244-248 5 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Adult 100%
  • Patient 80%
  • Therapeutic Procedure 80%
  • Pediatrics Patient 80%
  • Chemotherapy 80%
  3 被引用数 (Scopus)
• 2014

  Combination of bortezomib, thalidomide, and dexamethasone (VTD) as a consolidation therapy after autologous stem cell transplantation for symptomatic multiple myeloma in Japanese patients

  Takashima, S., Miyamoto, T., Kadowaki, M., Ito, Y., Aoki, T., Takase, K., Shima, T., Yoshimoto, G., Kato, K., Muta, T., Shiratsuchi, M., Takenaka, K., Iwasaki, H., Teshima, T., Kamimura, T. & Akashi, K., 8月 2014, In: International journal of hematology. 100, 2, p. 159-164 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Multiple Myeloma 100%
  • Dexamethasone 75%
  • Bortezomib 75%
  • Thalidomide 75%
  • Peripheral Neuropathy 50%
  6 被引用数 (Scopus)

• The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment

  Iwamoto, C., Takenaka, K., Urata, S., Yamauchi, T., Shima, T., Kuriyama, T., Daitoku, S., Saito, Y., Miyamoto, T., Iwasaki, H., Kitabayashi, I., Itoh, K., Kishimoto, J., Kohda, D., Matozaki, T. & Akashi, K., 3月 2014, In: Experimental Hematology. 42, 3, p. 163-171.e1

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • CD47 100%
  • Human Cell 66%
  • Engraftment 50%
  • Phagocytosis 33%
  • Binding Affinity 33%
  33 被引用数 (Scopus)

• The ordered acquisition of Class II and Class I mutations directs formation of human t(8;21) acute myelogenous leukemia stem cell

  Shima, T., Miyamoto, T., Kikushige, Y., Yuda, J., Tochigi, T., Yoshimoto, G., Kato, K., Takenaka, K., Iwasaki, H., Mizuno, S., Goto, N. & Akashi, K., 11月 1 2014, In: Experimental Hematology. 42, 11, p. 955-965.e5

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Stem Cell 100%
  • Mutant 37%
  • Mutation 37%
  • Hematopoietic Stem Cell 37%
  • Wild Type 12%
  19 被引用数 (Scopus)

• TLR7 ligand augments GM-CSF-initiated antitumor immunity through activation of plasmacytoid dendritic cells

  Narusawa, M., Inoue, H., Sakamoto, C., Matsumura, Y., Takahashi, A., Inoue, T., Watanabe, A., Miyamoto, S., Miura, Y., Hijikata, Y., Tanaka, Y., Inoue, M., Takayama, K., Okazaki, T., Hasegawa, M., Nakanishi, Y. & Tani, K., 6月 2014, In: Cancer Immunology Research. 2, 6, p. 568-580 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Granulocyte Macrophage Colony-Stimulating Factor 100%
  • Mouse 83%
  • Immunity 50%
  • Lung 50%
  • Interferon Type I 33%
  14 被引用数 (Scopus)
• 2013

  A novel filtration method for cord blood processing using a polyester fabric filter

  Shima, T., Forraz, N., Sato, N., Yamauchi, T., Iwasaki, H., Takenaka, K., Akashi, K., Mcguckin, C. & Teshima, T., 8月 2013, In: International Journal of Laboratory Hematology. 35, 4, p. 436-446 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Cord Blood 100%
  • Cells 71%
  • Processing 42%
  • Filtration 28%
  • Polyester 28%
  3 被引用数 (Scopus)

• Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment

  Yamauchi, T., Takenaka, K., Urata, S., Shima, T., Kikushige, Y., Tokuyama, T., Iwamoto, C., Nishihara, M., Iwasaki, H., Miyamoto, T., Honma, N., Nakao, M., Matozaki, T. & Akashi, K., 2月 21 2013, In: Blood. 121, 8, p. 1316-1325 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Mouse 100%
  • Human Cell 60%
  • Engraftment 40%
  • Xenograft 40%
  • Phenotype 20%
  104 被引用数 (Scopus)

• Quantitation of hematogones at the time of engraftment is a useful prognostic indicator in allogeneic hematopoietic stem cell transplantation

  Shima, T., Miyamoto, T., Kikushige, Y., Mori, Y., Kamezaki, K., Takase, K., Henzan, H., Numata, A., Ito, Y., Takenaka, K., Iwasaki, H., Kamimura, T., Eto, T., Nagafuji, K., Teshima, T., Kato, K. & Akashi, K., 1月 31 2013, In: Blood. 121, 5, p. 840-848 9 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Patient 100%
  • Donor 100%
  • Bone Marrow 100%
  • B Cell 100%
  • Cells 75%
  25 被引用数 (Scopus)
• 2012

  [Development of novel immune therapies for solid tumors: phase I clinical trials in a single institute].

  Hijikata, Y., Murahashi-Iga, M., Okazaki, T., Tanaka, Y., Odaira, K., Okano, S., Hisano, T., Takahashi, A., Marumoto, T., Inoue, H. & Tani, K., 5月 2012, In: [Rinshō ketsueki] The Japanese journal of clinical hematology. 53, 5, p. 487-492 6 p.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読

• Absence of LTB4/BLT1 axis facilitates generation of mouse GM-CSF-induced long-lasting antitumor immunologic memory by enhancing innate and adaptive immune systems

  Yokota, Y., Inoue, H., Matsumura, Y., Nabeta, H., Narusawa, M., Watanabe, A., Sakamoto, C., Hijikata, Y., Iga-Murahashi, M., Takayama, K., Sasaki, F., Nakanishi, Y., Yokomizo, T. & Tani, K., 10月 25 2012, In: Blood. 120, 17, p. 3444-3454 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Granulocyte Macrophage Colony-Stimulating Factor 100%
  • Leukotriene B4 100%
  • Mouse 60%
  • T-Helper Cell 60%
  • Innate Immune System 40%
  18 被引用数 (Scopus)

• CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells

  Niiro, H., Jabbarzadeh-Tabrizi, S., Kikushige, Y., Shima, T., Noda, K., Ota, S. I., Tsuzuki, H., Inoue, Y., Arinobu, Y., Iwasaki, H., Shimoda, S., Baba, E., Tsukamoto, H., Horiuchi, T., Taniyama, T. & Akashi, K., 3月 8 2012, In: Blood. 119, 10, p. 2263-2273 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • B Cell 100%
  • Lineages 80%
  • Lymphoma 80%
  • B-Cell Receptor 70%
  • B Lymphocyte Receptor 70%
  15 被引用数 (Scopus)
• 2011

  Self-Renewing Hematopoietic Stem Cell Is the Primary Target in Pathogenesis of Human Chronic Lymphocytic Leukemia

  Kikushige, Y., Ishikawa, F., Miyamoto, T., Shima, T., Urata, S., Yoshimoto, G., Mori, Y., Iino, T., Yamauchi, T., Eto, T., Niiro, H., Iwasaki, H., Takenaka, K. & Akashi, K., 8月 16 2011, In: Cancer Cell. 20, 2, p. 246-259 14 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • B-Cell Chronic Lymphocytic Leukemia 100%
  • B Cell 66%
  • Gene 50%
  • Clone 50%
  • Hematopoietic Stem Cell 33%
  234 被引用数 (Scopus)
• 2010

  [New strategies in anti-tumor immunotherapy].

  Murahashi, M., Hijikata, Y., Suehiro, Y., Inoue, H., Tanaka, Y., Shimoda, S., Marumoto, T., Okazai, T., Yoshida, K., Tsunoda, T. & Tani, K., 11月 2010, In: [Rinshō ketsueki] The Japanese journal of clinical hematology. 51, 11, p. 1654-1660 7 p.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読
  1 被引用数 (Scopus)

• Fabry disease exhibiting recurrent stroke and persistent inflammation

  Kikumoto, Y., Kai, Y., Morinaga, H., Iga-Murahashi, M., Matsuyama, M., Sasaki, T., Maruyama, H., Shimotori, M., Makino, H., Sugiyama, H. & Okayama, A., 2010, In: Internal Medicine. 49, 20, p. 2247-2252 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Apoplexy 100%
  • Stroke 100%
  • Patient 40%
  • Enzyme Replacement Therapy 40%
  • Serositis 20%
  15 被引用数 (Scopus)

• TIM-3 is a promising target to selectively kill acute myeloid leukemia stem cells

  Kikushige, Y., Shima, T., Takayanagi, S. I., Urata, S., Miyamoto, T., Iwasaki, H., Takenaka, K., Teshima, T., Tanaka, T., Inagaki, Y. & Akashi, K., 12月 3 2010, In: Cell stem cell. 7, 6, p. 708-717 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Myeloid 100%
  • Acute Myeloid Leukemia 100%
  • Intravenous Immunoglobulin 70%
  • Immunoglobulin 70%
  • Mucin 3 70%
  334 被引用数 (Scopus)
• 2009

  Disseminated tuberculosis following second unrelated cord blood transplantation for acute myelogenous leukemia

  Shima, T., Yoshimoto, G., Miyamoto, T., Yoshida, S., Kamezaki, K., Takenaka, K., Iwasaki, H., Harada, N., Nagafuji, K., Teshima, T., Shimono, N. & Akashi, K., 2月 2009, In: Transplant Infectious Disease. 11, 1, p. 75-77 3 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Cord Blood Stem Cell Transplantation 100%
  • Patient 50%
  • Engraftment 50%
  • Miliary Tuberculosis 50%
  • Acute Myeloid Leukemia 33%
  12 被引用数 (Scopus)

• FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation

  Yoshimoto, G., Miyamoto, T., Jabbarzadeh-Tabrizi, S., Iino, T., Rocnik, J. L., Kikushige, Y., Mori, Y., Shima, T., Iwasaki, H., Takenaka, K., Nagafuji, K., Mizuno, S. I., Niiro, H., Gilliland, G. D. & Akashi, K., 12月 3 2009, In: Blood. 114, 24, p. 5034-5043 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Myeloid 100%
  • FMS-Like Tyrosine Kinase 3 58%
  • Stem Cell 35%
  • STAT5 23%
  • Hematopoietic Stem Cell 17%
  185 被引用数 (Scopus)
• 2008

  An unexpected cause of a febrile patient with huge splenomegaly

  Nonami, A., Yamamoto, H., Nakamura, M., Nagafuji, K. & Teshima, T., 7月 2008, In: Clinical Rheumatology. 27, 7, p. 941-943 3 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Splenomegaly 100%
  • Patient 66%
  • Fever 50%
  • Diagnosis 33%
  • Differential Diagnosis 33%

• Construction of a high-performance human fetal liver-derived lentiviral cDNA library

  Kurita, R., Oikawa, T., Okada, M., Yokoo, T., Kurihara, Y., Honda, Y., Kageyama, R., Suehiro, Y., Okazaki, T., Iga, M., Miyoshi, H. & Tani, K., 12月 2008, In: Molecular and cellular biochemistry. 319, 1-2, p. 181-187 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Gene 100%
  • Liver 100%
  • Regenerative Medicine 100%
  • Nested Gene 100%
  • Protein 100%
  6 被引用数 (Scopus)

• Non-transmissible Sendai virus encoding granulocyte macrophage colony-stimulating factor is a novel and potent vector system for producing autologous tumor vaccines

  Inoue, H., Iga, M., Nabeta, H., Yokoo, T., Suehiro, Y., Okano, S., Inoue, M., Kinoh, H., Katagiri, T., Takayama, K., Yonemitsu, Y., Hasegawa, M., Nakamura, Y., Nakanishi, Y. & Tani, K., 2008, In: Cancer Science. 99, 11, p. 2315-2326 12 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Sendai Virus 100%
  • Mouse 72%
  • Cells 63%
  • Granulocyte Macrophage Colony-Stimulating Factor 63%
  • Carcinoma Cell 27%
  17 被引用数 (Scopus)

• Reinforcement tumor immunotherapy using RNF43 peptide pulse dendritic cells and activated CTL clone for advanced solid tumor patient

  Hisano, T., Takasugi, K., Iga, M., Kurita, R., Yoshikawa, Y. & Tani, K., 9月 2008, In: Biotherapy. 22, 5, p. 332-337 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Cytotoxic T-Cell 100%
  • Peptide 80%
  • Patient 40%
  • In Vitro 40%
  • Regulatory T Cell 40%

• Successful treatment of parainfluenza virus 3 pneumonia with oral ribavirin and methylprednisolone in a bone marrow transplant recipient

  Shima, T., Yoshimoto, G., Nonami, A., Yoshida, S., Kamezaki, K., Iwasaki, H., Takenaka, K., Miyamoto, T., Harada, N., Teshima, T., Akashi, K. & Nagafuji, K., 10月 2008, In: International journal of hematology. 88, 3, p. 336-340 5 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Ribavirin 100%
  • Pneumonia 80%
  • Methylprednisolone 60%
  • Serositis 40%
  • Patient 40%
  27 被引用数 (Scopus)

• Unusual radiological findings of Fasciola hepatica infection with huge cystic and multilocular lesions

  Maeda, T., Yamada, H., Akao, N., Iga, M., Endo, T., Koibuchi, T., Nakamura, T., Odawara, T., Iwamoto, A. & Fujii, T., 2008, In: Internal Medicine. 47, 5, p. 449-452 4 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Fascioliasis 100%
  • Lesion 66%
  • Radiological Finding 66%
  • Liver Polycystic Disease 66%
  • Differential Diagnosis 33%
  11 被引用数 (Scopus)
• 2007

  In vitro translation to study HIV protease activity

  Matsuda, Z., Iga, M., Miyauchi, K., Komano, J., Morishita, K., Okayama, A. & Tsubouchi, H., 4月 4 2007, In Vitro Transcription and Translation Protocols: Second Edition. Grandi, G. (ed.). p. 135-149 15 p. (Methods in Molecular Biology; vol. 375).

  研究成果: 書籍/レポート タイプへの寄稿 › 章

  • Human Immunodeficiency Virus Proteinase 100%
  • Proteinase 60%
  • Drug 20%
  • Chemotherapy 20%
  • Virus 20%
  2 被引用数 (Scopus)