What does pain or discomfort in irritable bowel syndrome mean?

Masanori Handa, Hideyuki Nukina, Katsumi Ando, Chiharu Kubo

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Despite many studies on pain of functional gastrointestinal disorders (FGID), the pain mechanism of FGID is not well understood, and pain treatment of FGID is not established. Following our former functional dyspepsia (FD) study, we proposed two subgroups of patients with irritable bowel syndrome (IBS), pain and discomfort (not pain). The duration of disease of discomfort IBS patients was longer than that of pain IBS patients (P < 0.05) The rate of anxiety disorder of pain IBS patients tended to be higher than that of discomfort IBS patients (P = 0.07172). Fifteen (15.2%) of 99 pain IBS patients and 1 (3.4%) of 29 discomfort IBS patients overlapped FD (P < 0.1). We expected that a common psychosocial mechanism would influence both pain dyspepsia patients and pain IBS patients, however, there were some differences between these FGID patients with pain. Anxiety in IBS patients with lower gastrointestinal pain seems to be important in their treatment.

Original languageEnglish
Pages (from-to)575-578
Number of pages4
JournalDigestive Diseases and Sciences
Issue number4
Publication statusPublished - Apr 2004
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Physiology
  • Gastroenterology


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