Well-differentiated adenocarcinoma of the gallbladder with intratumoral cystic components due to abundant mucin production: A mimicker of adenomyomatosis

Kengo Yoshimitsu, Hiroyuki Irie, Hitoshi Aibe, Tsuyoshi Tajima, Akihiro Nishie, Yoshiki Asayama, Kunishige Matake, Kouji Yamaguchi, Shuji Matsuura, Hiroshi Honda

    Research output: Contribution to journalArticlepeer-review

    29 Citations (Scopus)

    Abstract

    The prevalence and etiology of the cystic components within gallbladder carcinomas as seen on MR images were evaluated. A retrospective review of MR images was performed for 35 proven gallbladder carcinomas in search of radiologically detectable intratumoral cystic components. The pathologic specimens were meticulously reviewed to determine the etiology. MR images of 31 adenomyomatoses were also reviewed for comparison to clarify the difference in MR features between these two entities. Three cases out of 35 proven gallbladder carcinomas were found to have intratumoral cystic components. They were all well-differentiated adenocarcinomas, and the cystic components consisted of dilated neoplastic glands filled with abundant mucin pool. Adenomyomatosis tended to have more and rounded cystic components (Rokitansky-Aschoff sinuses) lined in a linear fashion and were flat-elevated in shape, smaller in size and had a regular surface, as compared to the three carcinomas. Although rare, radiologists need to be aware that well-differentiated gallbladder carcinoma with mucin production can have cystic components, which may mimic adenomyomatosis. Careful interpretation of MR images may provide useful information in the differentiation of these two entities.

    Original languageEnglish
    Pages (from-to)229-233
    Number of pages5
    JournalEuropean Radiology
    Volume15
    Issue number2
    DOIs
    Publication statusPublished - Feb 2005

    All Science Journal Classification (ASJC) codes

    • Radiology Nuclear Medicine and imaging

    Fingerprint

    Dive into the research topics of 'Well-differentiated adenocarcinoma of the gallbladder with intratumoral cystic components due to abundant mucin production: A mimicker of adenomyomatosis'. Together they form a unique fingerprint.

    Cite this