Wear reduction by functional protein boundary film on Poly(vinyl alcohol) hydrogel

K. Nakashima, Y. Sawae, T. Murakami

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Poly(vinyl alcohol) (PVA) hydrogel is a candidate material for artificial cartilage of joint prostheses. From previous researches[1-4] it is shown that the wear of PVA hydrogel depends on the concentration of proteins in lubricants. Therefore it is considered that the adsorbed film formation by protein of albumin or γ-globulin influences upon the wear grade of PVA hydrogel. The remaining film of proteins on the glass plate was observed in fluorescence microscope. The adsorption condition of albumin and γ-globulin was different. The adsorbed film with effective reduction of the wear showed cooperative stratification of albumin and γ-globulin, but the condition of increased the wear showed separation of albumin and γ-globulin. Consequently, to reduce the wear of PVA hydrogel, cooperative stratification layers are effective.

Original languageEnglish
Title of host publicationProceedings of the World Tribology Congress III - 2005
PublisherAmerican Society of Mechanical Engineers
Number of pages2
ISBN (Print)0791842029, 9780791842027
Publication statusPublished - 2005
Event2005 World Tribology Congress III - Washington, D.C., United States
Duration: Sept 12 2005Sept 16 2005

Publication series

NameProceedings of the World Tribology Congress III - 2005


Other2005 World Tribology Congress III
Country/TerritoryUnited States
CityWashington, D.C.

All Science Journal Classification (ASJC) codes

  • General Engineering


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