Usefulness of18F-fluorodeoxyglucose positron emission tomography as predictor of distant metastasis in preoperative carbon-ion radiotherapy for pancreatic cancer

Makoto Shinoto; Shigeru Yamada; Kyosan Yoshikawa; Shigeo Yasuda; Yoshiyuki Shioyama; Hiroshi Honda; Tadashi Kamada; Hirohiko Tsujii

Usefulness of¹⁸F-fluorodeoxyglucose positron emission tomography as predictor of distant metastasis in preoperative carbon-ion radiotherapy for pancreatic cancer

Makoto Shinoto, Shigeru Yamada, Kyosan Yoshikawa, Shigeo Yasuda, Yoshiyuki Shioyama, Hiroshi Honda, Tadashi Kamada, Hirohiko Tsujii

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Aim: The purpose of this study was to evaluate the role of FDG-PET regarding the indication of preoperative carbon-ion radiotherapy (CIRT) for pancreatic cancer patients. Patients and Methods: Patients with resectable pancreatic cancer underwent preoperative CIRT. The impact of baseline SUV _max on prognosis for patients was assessed by analyzing correlations with distant metastasis-free survival (DMFS) and overall survival (OS). Results: Out of 21 patients, local recurrence was observed in no patient and distant metastasis was found in 13 patients (62%). 1-year DMFS and OS in low-SUV _max group were significantly higher than those in high-SUV _max group (91% vs. 20% and 91% vs. 56%). SUV_max was significantly correlated with DMFS and OS. Conclusion: Our data indicated a significant correlation between SUV_max and DMFS. FDG-PET might be useful for determining the indication of preoperative short-course CIRT for patients with resectable pancreatic cancer.

Original language	English
Pages (from-to)	5579-5584
Number of pages	6
Journal	Anticancer research
Volume	33
Issue number	12
Publication status	Published - Dec 2013

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Usefulness of18F-fluorodeoxyglucose positron emission tomography as predictor of distant metastasis in preoperative carbon-ion radiotherapy for pancreatic cancer",

abstract = "Aim: The purpose of this study was to evaluate the role of FDG-PET regarding the indication of preoperative carbon-ion radiotherapy (CIRT) for pancreatic cancer patients. Patients and Methods: Patients with resectable pancreatic cancer underwent preoperative CIRT. The impact of baseline SUV max on prognosis for patients was assessed by analyzing correlations with distant metastasis-free survival (DMFS) and overall survival (OS). Results: Out of 21 patients, local recurrence was observed in no patient and distant metastasis was found in 13 patients (62%). 1-year DMFS and OS in low-SUV max group were significantly higher than those in high-SUV max group (91% vs. 20% and 91% vs. 56%). SUVmax was significantly correlated with DMFS and OS. Conclusion: Our data indicated a significant correlation between SUVmax and DMFS. FDG-PET might be useful for determining the indication of preoperative short-course CIRT for patients with resectable pancreatic cancer.",

author = "Makoto Shinoto and Shigeru Yamada and Kyosan Yoshikawa and Shigeo Yasuda and Yoshiyuki Shioyama and Hiroshi Honda and Tadashi Kamada and Hirohiko Tsujii",

year = "2013",

month = dec,

language = "English",

volume = "33",

pages = "5579--5584",

journal = "Anticancer research",

issn = "0250-7005",

publisher = "International Institute of Anticancer Research",

number = "12",

}

TY - JOUR

T1 - Usefulness of18F-fluorodeoxyglucose positron emission tomography as predictor of distant metastasis in preoperative carbon-ion radiotherapy for pancreatic cancer

AU - Shinoto, Makoto

AU - Yamada, Shigeru

AU - Yoshikawa, Kyosan

AU - Yasuda, Shigeo

AU - Shioyama, Yoshiyuki

AU - Honda, Hiroshi

AU - Kamada, Tadashi

AU - Tsujii, Hirohiko

PY - 2013/12

Y1 - 2013/12

N2 - Aim: The purpose of this study was to evaluate the role of FDG-PET regarding the indication of preoperative carbon-ion radiotherapy (CIRT) for pancreatic cancer patients. Patients and Methods: Patients with resectable pancreatic cancer underwent preoperative CIRT. The impact of baseline SUV max on prognosis for patients was assessed by analyzing correlations with distant metastasis-free survival (DMFS) and overall survival (OS). Results: Out of 21 patients, local recurrence was observed in no patient and distant metastasis was found in 13 patients (62%). 1-year DMFS and OS in low-SUV max group were significantly higher than those in high-SUV max group (91% vs. 20% and 91% vs. 56%). SUVmax was significantly correlated with DMFS and OS. Conclusion: Our data indicated a significant correlation between SUVmax and DMFS. FDG-PET might be useful for determining the indication of preoperative short-course CIRT for patients with resectable pancreatic cancer.

AB - Aim: The purpose of this study was to evaluate the role of FDG-PET regarding the indication of preoperative carbon-ion radiotherapy (CIRT) for pancreatic cancer patients. Patients and Methods: Patients with resectable pancreatic cancer underwent preoperative CIRT. The impact of baseline SUV max on prognosis for patients was assessed by analyzing correlations with distant metastasis-free survival (DMFS) and overall survival (OS). Results: Out of 21 patients, local recurrence was observed in no patient and distant metastasis was found in 13 patients (62%). 1-year DMFS and OS in low-SUV max group were significantly higher than those in high-SUV max group (91% vs. 20% and 91% vs. 56%). SUVmax was significantly correlated with DMFS and OS. Conclusion: Our data indicated a significant correlation between SUVmax and DMFS. FDG-PET might be useful for determining the indication of preoperative short-course CIRT for patients with resectable pancreatic cancer.

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AN - SCOPUS:84891446339

SN - 0250-7005

VL - 33

SP - 5579

EP - 5584

JO - Anticancer research

JF - Anticancer research

IS - 12

ER -

Usefulness of¹⁸F-fluorodeoxyglucose positron emission tomography as predictor of distant metastasis in preoperative carbon-ion radiotherapy for pancreatic cancer

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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