[Usefulness of ARB in heart failure].

Hiroyuki Tsutsui

Research output: Contribution to journalReview articlepeer-review


An angiotensin receptor blocker (ARB) is recommended as an alternative in patients with heart failure and left ventricular ejection fraction less than 40% intolerant of an ACE inhibitor. In these patients, an ARB reduces the risk of death from a cardiovascularcause or hospital admission for worsening heart failure. It is also recommended in patients with heart failure who remain symptomatic despite optimal treatment with an ACE inhibitor and beta-blocker. Treatment with an ARB improves ventricular function and patient well-being, and reduces hospital admission for worsening heart failure. In patients with heart failure and preserved left ventricular ejection fraction, although no treatment has yet been shown, convincingly, to reduce morbidity and mortality, adequate treatment of hypertension is important and ARB is considered to be able t o reduce the risk of admissionsfor heart failure.

Original languageEnglish
Pages (from-to)751-757
Number of pages7
JournalNippon rinsho. Japanese journal of clinical medicine
Issue number4
Publication statusPublished - Apr 2009
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Medicine


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