Use of ionic liquids in a lipase-facilitated supported liquid membrane

Eijiro Miyako, Tatsuo Maruyama, Noriho Kamiya, Masahiro Goto

Research output: Contribution to journalArticlepeer-review

66 Citations (Scopus)


A lipase-facilitated transport of 4-phenoxybutyric acid, 3-phenoxypropionic acid, 2-phenylpropionic acid, 2-phenoxybutyric acid, mandelic acid and 2-amino-2-phenylbutyric acid was carried out using a supported liquid membrane based on room temperature ionic liquids. There were marked differences in the permeate fluxes of various organic acids due to the substrate specificity of the lipases. The maximum permeate flux (44 x 10-2 mmol cm-2 x h) was obtained using 4-phenoxybutyric acid as the substrate and 1-n-butyl-3-methylimidazolium hexafluorophosphate as the liquid membrane phase.

Original languageEnglish
Pages (from-to)805-808
Number of pages4
JournalBiotechnology letters
Issue number10
Publication statusPublished - May 2003

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology


Dive into the research topics of 'Use of ionic liquids in a lipase-facilitated supported liquid membrane'. Together they form a unique fingerprint.

Cite this