UCST-type cononsolvency behavior of poly(2-methacryloxyethyl phosphorylcholine) in the mixture of water and ethanol

Yasuhiro Matsuda; Motoyasu Kobayashi; Masahiko Annaka; Kazuhiko Ishihara; Atsushi Takahara

doi:10.1295/polymj.PJ2008009

UCST-type cononsolvency behavior of poly(2-methacryloxyethyl phosphorylcholine) in the mixture of water and ethanol

Yasuhiro Matsuda, Motoyasu Kobayashi, Masahiko Annaka, Kazuhiko Ishihara, Atsushi Takahara

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

A study was conducted for turbimetry and dynamic light scattering (DLS) measurements of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) in the mixture of water and ethanol. PMPC has positive and negative charge in its phosphorylcholine group. PMPC never shrinks in aqueous solution with low ionic strength and network of water molecular formed by hydrogen bonds remain unchanged. PMPC is used for medical materials for its high hydrophilic properties and high biocompatibility. PMPC was synthesized by atom transfer radial polymerization from the corresponding monomer. The size exclusion chromatography (SEC) was used to determine the molecular weight of PMPC samples. The study found that with phase separation, water and alcohols can form hydrogen bonds, which decreased the enthalpy of the system and entropy of PMPC decreased by the precipitation.

Original language	English
Pages (from-to)	479-483
Number of pages	5
Journal	Polymer Journal
Volume	40
Issue number	5
DOIs	https://doi.org/10.1295/polymj.PJ2008009
Publication status	Published - 2008

All Science Journal Classification (ASJC) codes

Polymers and Plastics
Materials Chemistry

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10.1295/polymj.PJ2008009

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title = "UCST-type cononsolvency behavior of poly(2-methacryloxyethyl phosphorylcholine) in the mixture of water and ethanol",

abstract = "A study was conducted for turbimetry and dynamic light scattering (DLS) measurements of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) in the mixture of water and ethanol. PMPC has positive and negative charge in its phosphorylcholine group. PMPC never shrinks in aqueous solution with low ionic strength and network of water molecular formed by hydrogen bonds remain unchanged. PMPC is used for medical materials for its high hydrophilic properties and high biocompatibility. PMPC was synthesized by atom transfer radial polymerization from the corresponding monomer. The size exclusion chromatography (SEC) was used to determine the molecular weight of PMPC samples. The study found that with phase separation, water and alcohols can form hydrogen bonds, which decreased the enthalpy of the system and entropy of PMPC decreased by the precipitation.",

author = "Yasuhiro Matsuda and Motoyasu Kobayashi and Masahiko Annaka and Kazuhiko Ishihara and Atsushi Takahara",

note = "Funding Information: Acknowledgment. The present work was supported by a Grant-in-Aid for the Global COE Program {\textquoteleft}{\textquoteleft}Science for Future Molecular Systems{\textquoteright}{\textquoteright} from the Ministry of Education, Culture, Science, Sports and Technology of Japan. This work was also partially supported by the Sasakawa Scientific Research Grant from The Japan Science Society.",

year = "2008",

doi = "10.1295/polymj.PJ2008009",

language = "English",

volume = "40",

pages = "479--483",

journal = "Polymer Journal",

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T1 - UCST-type cononsolvency behavior of poly(2-methacryloxyethyl phosphorylcholine) in the mixture of water and ethanol

AU - Matsuda, Yasuhiro

AU - Kobayashi, Motoyasu

AU - Annaka, Masahiko

AU - Ishihara, Kazuhiko

AU - Takahara, Atsushi

N1 - Funding Information: Acknowledgment. The present work was supported by a Grant-in-Aid for the Global COE Program ‘‘Science for Future Molecular Systems’’ from the Ministry of Education, Culture, Science, Sports and Technology of Japan. This work was also partially supported by the Sasakawa Scientific Research Grant from The Japan Science Society.

PY - 2008

Y1 - 2008

N2 - A study was conducted for turbimetry and dynamic light scattering (DLS) measurements of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) in the mixture of water and ethanol. PMPC has positive and negative charge in its phosphorylcholine group. PMPC never shrinks in aqueous solution with low ionic strength and network of water molecular formed by hydrogen bonds remain unchanged. PMPC is used for medical materials for its high hydrophilic properties and high biocompatibility. PMPC was synthesized by atom transfer radial polymerization from the corresponding monomer. The size exclusion chromatography (SEC) was used to determine the molecular weight of PMPC samples. The study found that with phase separation, water and alcohols can form hydrogen bonds, which decreased the enthalpy of the system and entropy of PMPC decreased by the precipitation.

AB - A study was conducted for turbimetry and dynamic light scattering (DLS) measurements of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) in the mixture of water and ethanol. PMPC has positive and negative charge in its phosphorylcholine group. PMPC never shrinks in aqueous solution with low ionic strength and network of water molecular formed by hydrogen bonds remain unchanged. PMPC is used for medical materials for its high hydrophilic properties and high biocompatibility. PMPC was synthesized by atom transfer radial polymerization from the corresponding monomer. The size exclusion chromatography (SEC) was used to determine the molecular weight of PMPC samples. The study found that with phase separation, water and alcohols can form hydrogen bonds, which decreased the enthalpy of the system and entropy of PMPC decreased by the precipitation.

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DO - 10.1295/polymj.PJ2008009

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JO - Polymer Journal

JF - Polymer Journal

IS - 5

ER -

UCST-type cononsolvency behavior of poly(2-methacryloxyethyl phosphorylcholine) in the mixture of water and ethanol

Abstract

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