TY - JOUR
T1 - Two-dimensional magnetic nanoparticle imaging using multiple magnetic sensors based on amplitude modulation
AU - Sasayama, Teruyoshi
AU - Yoshida, Takashi
AU - Enpuku, Keiji
N1 - Funding Information:
This work was supported by the Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Young Scientists (B) [grant number JP16K18114 ] and Young Scientists [grant number JP19K14996]; and by the Mazda Foundation. Mark Kurban from Edanz Group ( www.edanzediting.com/ac ) edited a draft of this manuscript.
Publisher Copyright:
© 2020 Elsevier B.V.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - We propose an imaging system for magnetic nanoparticles (MNPs) using multiple magnetic sensors based on amplitude modulation. The system was used to obtain two-dimensional images of two MNP samples spaced 15 mm apart at a depth of 30 mm. An AC magnetic field was used at an operating frequency of 5.4 kHz, and a third-harmonic signal generated by the MNP samples was detected using 16 pickup coils. To increase the position information of the MNP samples, the amplitude of the AC magnetic field was changed from 0.24 to 4.8 mT. The third-harmonic signals were subsequently analyzed using nonnegative least squares to image the MNP samples. The results show that the positions of the two MNP samples were estimated with good accuracy.
AB - We propose an imaging system for magnetic nanoparticles (MNPs) using multiple magnetic sensors based on amplitude modulation. The system was used to obtain two-dimensional images of two MNP samples spaced 15 mm apart at a depth of 30 mm. An AC magnetic field was used at an operating frequency of 5.4 kHz, and a third-harmonic signal generated by the MNP samples was detected using 16 pickup coils. To increase the position information of the MNP samples, the amplitude of the AC magnetic field was changed from 0.24 to 4.8 mT. The third-harmonic signals were subsequently analyzed using nonnegative least squares to image the MNP samples. The results show that the positions of the two MNP samples were estimated with good accuracy.
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U2 - 10.1016/j.jmmm.2020.166765
DO - 10.1016/j.jmmm.2020.166765
M3 - Article
AN - SCOPUS:85081981162
SN - 0304-8853
VL - 505
JO - Journal of Magnetism and Magnetic Materials
JF - Journal of Magnetism and Magnetic Materials
M1 - 166765
ER -