Transplantation of neural stem cells with valproate for spinal cord injury

Masahiko Abematsu; Kinichi Nakashima

doi:10.1007/978-4-431-54502-6_20

Transplantation of neural stem cells with valproate for spinal cord injury

Masahiko Abematsu, Kinichi Nakashima

Stem Cell Biology and Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Citation (Scopus)

Abstract

The regenerative capacity of an injured spinal cord is limited, and once paralysis occurs, it is difficult to improve the situation. We have developed a treatment method called the HINT method (HDAC Inhibitor and Neural stem cell Transplantation) that improves hind limb motor functionality in mice with severe spinal cord injuries by using a combination of antiepileptic drugs and neural stem cells. This chapter will introduce you to the new neural damage reconstruction mechanism employed in the HINT method.

Original language	English
Title of host publication	Neuroprotection and Regeneration of the Spinal Cord
Publisher	Springer Japan
Pages	247-253
Number of pages	7
Volume	9784431545026
ISBN (Electronic)	9784431545026
ISBN (Print)	4431545018, 9784431545019
DOIs	https://doi.org/10.1007/978-4-431-54502-6_20
Publication status	Published - Nov 1 2014

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.1007/978-4-431-54502-6_20

Cite this

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Transplantation of neural stem cells with valproate for spinal cord injury

Abstract

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