@article{5cc2f719bb614d8b9f06f037a438ae18,
title = "Transient Protection of Organic Azides from Click Reactions with Alkynes by Phosphazide Formation",
abstract = "A method for protecting organic azides from click reactions with alkynes is reported. Treatment of azides with Amphos affords phosphazides, which are stable under click reaction conditions and are easily converted back to azides by treatment with elemental sulfur. Thus, the method allows for facile modification of azide compounds via site-selective click reactions.",
author = "Tomohiro Meguro and Suguru Yoshida and Kazunobu Igawa and Katsuhiko Tomooka and Takamitsu Hosoya",
note = "Funding Information: This work was supported by the Japan Agency for Medical Research and Development (AMED) under Grant Nos. JP18am0101098 (Platform Project for Supporting Drug Discovery and Life Science Research (BINDS)) and JP18am0301024 (Basic Science and Platform Technology Program for Innovative Biological Medicine); the Cooperative Research Project of the Research Center for Biomedical Engineering; the Research Program of “Five-Star Alliance” in “NJRC Mater. & Dev.”; JSPS KAKENHI Grant Nos. 15H03118 and 18H02104 (B; T.H.), 16H01133 and 18H04386 (Middle Molecular Strategy; T.H.), 17H06414 (Organelle Zone; T.H.), 26350971 (C; S.Y.), 18J11113 (JSPS Research Fellow; T.M.); and the Naito Foundation (S.Y.).",
year = "2018",
month = jul,
day = "6",
doi = "10.1021/acs.orglett.8b01692",
language = "English",
volume = "20",
pages = "4126--4130",
journal = "Organic letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "13",
}