Topical tacrolimus in the management of atopic dermatitis in Japan

Masutaka Furue, Hiroshi Uchi, Yoichi Moroi, Sachiko Ogawa, Takeshi Nakahara, Kazunori Urabe

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)


Atopic dermatitis (AD) is a common, chronic, relapsing, severely pruritic, eczematous skin disease. Topical steroids are the mainstay of treatment. However, the adverse effects of steroids on hormonal function are the major obstacle for their use as long-term topical therapy. Topical calcineurin inhibitors, such as tacrolimus, not only complement existing treatment options but also overcome some of the drawbacks of topical steroid therapy and fulfill the long-term needs of patients in preventing disease progression. Short- and long-term efficacy and safety of topical tacrolimus has been widely recognized and it is also accepted as a first-line treatment for the inflammation of AD. In order to reduce the possible long-term adverse effects, it is important to monitor the clinical dose in daily clinics.

Original languageEnglish
Pages (from-to)118-126
Number of pages9
JournalDermatologic Therapy
Issue number2
Publication statusPublished - Mar 2006

All Science Journal Classification (ASJC) codes

  • Dermatology


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