Topical tacrolimus as treatment of atopic dermatitis

Masutaka Furue, Satoshi Takeuchi

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)


Atopic dermatitis (AD) is a common, chronic, relapsing, severely pruritic, eczematous skin disease. The mainstays of treatment for AD are topical tacrolimus and topical steroids. Tacrolimus, a calcineurin inhibitor, not only complements existing treatment options but also overcomes some of the drawbacks of topical steroid therapy when given topically and thus meets the long-term needs of patients in preventing disease progression. Topical tacrolimus has been widely recognized in terms of its short- and long-term efficacies and safety, and it is also accepted as a first-line treatment for inflammation in AD. The recent proactive use of topical tacrolimus may emphasize a long-term benefit of this calcineurin inhibitor for AD treatment. To reduce possible long-term adverse effects, it is important to monitor its topical doses in daily clinics.

Original languageEnglish
Pages (from-to)161-166
Number of pages6
JournalClinical, Cosmetic and Investigational Dermatology
Publication statusPublished - 2009

All Science Journal Classification (ASJC) codes

  • Dermatology


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