Tissue engineering using magnetite nanoparticles

Research output: Chapter in Book/Report/Conference proceedingChapter

77 Citations (Scopus)

Abstract

The major advantage of magnetic manipulation is "remote control." Magnetic labeling of cells with magnetic nanoparticles enables the manipulation of cells and also the control of cell functions by applying an external magnetic field. "Functional" magnetite nanoparticles were developed for cell manipulation using magnetic force, and the magnetite nanoparticles were applied to tissue-engineering processes, which are designated as magnetic force-based tissue engineering (Mag-TE). This chapter reviews recent progress in Mag-TE techniques, and the principles and utilities of the applications are discussed. This review covers three topics of magnetic cell manipulation using magnetite nanoparticles, including a magnetic force-based gene transfer technique (magnetofection), magnetic cell patterning using functional magnetite nanoparticles and micro-patterned magnetic field gradient concentrators, and finally applications for fabrication of tissue-like constructs in skin, liver, and muscle tissue engineering.

Original languageEnglish
Title of host publicationProgress in Molecular Biology and Translational Science
PublisherElsevier B.V.
Pages355-395
Number of pages41
DOIs
Publication statusPublished - 2011

Publication series

NameProgress in Molecular Biology and Translational Science
Volume104
ISSN (Print)1877-1173

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Molecular Biology

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