Three nights leg thermal therapy could improve sleep quality in patients with chronic heart failure

Hiroyuki Sawatari, Mari K. Nishizaka, Mami Miyazono, Shin ichi Ando, Shujiro Inoue, Masao Takemoto, Takafumi Sakamoto, Daisuke Goto, Tomoo Furumoto, Shintaro Kinugawa, Nobuko Hashiguchi, Anita Rahmawati, Hiroaki Chishaki, Tomoko Ohkusa, Chie Magota, Hiroyuki Tsutsui, Akiko Chishaki

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Sleep quality is often impaired in patients with chronic heart failure (HF), which may worsen their quality of life and even prognosis. Leg thermal therapy (LTT), topical leg warming, has been shown to improve endothelial function, oxidative stress, and cardiac function in patients with HF. However, its short-term influence to sleep quality has not been evaluated in HF patients. Eighteen of 23 patients with stable HF received LTT (15 min of warming at 45 °C and 30 min of insulation) at bedtime for 3 consecutive nights and 5 patients served as control. Subjective sleep quality was evaluated by St. Mary’s Hospital Sleep Questionnaire, Oguri–Shirakawa–Azumi Sleep Inventory, and Epworth sleepiness scale, and also objectively evaluated by polysomnography. LTT significantly improved subjective sleep quality indicated by depth of sleep (p < 0.01), sleep duration (p < 0.05), number of awaking (p < 0.01), nap duration (p < 0.01), sleep quality (p < 0.05), and sleep satisfaction (p < 0.05). It was also objectively affirmed by a slight but significant decrease of sleep stage N1 (p < 0.01), and increase in sleep stage N2 (p < 0.05). No significant changes occurred in the controls. Hence, the short-term LTT could improve subjective and objective sleep quality in patients with HF. LTT can be a complimentary therapy to improve sleep quality in these patients.

Original languageEnglish
Pages (from-to)155-162
Number of pages8
JournalHeart and Vessels
Issue number2
Publication statusPublished - Feb 1 2018

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine


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