A 21-year-old man, who had previously undergone a total resection for a retroperitoneal ganglioneuroblastoma at 7 months of age, was revealed to have a thoracic paravertebral ganglioneuroma, in which immunohistochemical expression of neuron-specific enolase and neurofilament was noted. Furthermore, immunohistochemical expression of TrkA, which is a high-affinity receptor for nerve growth factor, was evident. Although the exact histogenesis remains uncertain. TrkA was considered to be involved in the development of this thoracic paravertebral tumor.
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Clinical Neurology