Thermal cyclization of nonconjugated aryl-yne-carbodiimide furnishing a dibenzonaphthyridine derivative

Hidenori Kimura; Kohei Torikai; Ikuo Ueda

doi:10.1248/cpb.57.393

Thermal cyclization of nonconjugated aryl-yne-carbodiimide furnishing a dibenzonaphthyridine derivative

Hidenori Kimura, Kohei Torikai, Ikuo Ueda

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

The reagent-free C²-C⁷ thermal cyclization of a nonconjugated aryl-yne-carbodiimide yielded a dibenzo- [b,g][1,8]naphthyridine derivative, whose congeners are known to possess fascinating pharmacological properties. This is the first heteroaromatic compound prepared by the thermal cycloaromatization of "nonconjugated" aryl-ynes.

Original language	English
Pages (from-to)	393-396
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	57
Issue number	4
DOIs	https://doi.org/10.1248/cpb.57.393
Publication status	Published - 2009
Externally published	Yes

All Science Journal Classification (ASJC) codes

Chemistry(all)
Drug Discovery

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author = "Hidenori Kimura and Kohei Torikai and Ikuo Ueda",

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AU - Torikai, Kohei

AU - Ueda, Ikuo

PY - 2009

Y1 - 2009

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AB - The reagent-free C2-C7 thermal cyclization of a nonconjugated aryl-yne-carbodiimide yielded a dibenzo- [b,g][1,8]naphthyridine derivative, whose congeners are known to possess fascinating pharmacological properties. This is the first heteroaromatic compound prepared by the thermal cycloaromatization of "nonconjugated" aryl-ynes.

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DO - 10.1248/cpb.57.393

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ER -

Thermal cyclization of nonconjugated aryl-yne-carbodiimide furnishing a dibenzonaphthyridine derivative

Abstract

All Science Journal Classification (ASJC) codes

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