Theoretical study of photo-physical properties of indolylmaleimide derivatives

Zilong Zheng, Yi Zhao, Manabu Nakazono, Shinkoh Nanbu

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6 Citations (Scopus)


Photo-physical properties of bromo-indolylmaleimide (IM-Br), indole-succinimide (IS), and their anions were theoretically investigated compared with the previous theoretical result for indolylmaleimide (IM) [Phys. Chem. Chem. Phys., 2010, 12, 9783]. The energies for the electronic excited states as well as the ground states were computed for these molecules using the multi-reference perturbation calculations based on the second order Rayleigh-Schrödinger perturbation theory (CASPT2) at the cc-pVDZ basis set level. The electron-accepting or electron-donating effect caused by bromine-substitution was discussed in the intra-molecular charge transfer (ICT) mechanism. The order of natural orbitals of the bromine-substituted monovalent anion with a deprotonated indole NH group (I (-)M-Br) was found to be rearranged by the effect of electron-donation, which leads to pseudo-crossing of the potential energy cures of the S 1 and S 2 states. The large stokes shift observed for I (-)M-Br was due to pseudo-crossing. Meanwhile, IM and IM-Br show abnormal deprotonation, which is explained by the charge distribution on the indole and maleimide moieties. Finally, the monovalent anions I (-)M-Br and I (-)M by a deprotonation of the indole NH end and the neutral IS were proposed to be the most feasible candidates corresponding to the experimental spectra in solution.

Original languageEnglish
Pages (from-to)3017-3024
Number of pages8
JournalPhysical Chemistry Chemical Physics
Issue number9
Publication statusPublished - Feb 28 2012

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry


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