The role of interleukin 15 in mounting an immune response against microbial infections

Yasunobu Yoshikai, Hitoshi Nishimura

Research output: Contribution to journalReview articlepeer-review

43 Citations (Scopus)

Abstract

Interleukin (IL)-15 is a recently described cytokine that resembles IL-2 in its biological activities, stimulating natural killer cells, T cells and B cells to proliferate, secrete cytokines, and exhibit increased cytotoxicities or produce antibody IL-15 also exerts unique functions such as stimulation of phagocytes, maintenance of mast cells and migration of activated/memory T cells. IL-15 is involved in protection against infections with a variety of microbes through not only activating innate immunity but also mounting adaptive immunity. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

Original languageEnglish
Pages (from-to)381-389
Number of pages9
JournalMicrobes and Infection
Volume2
Issue number4
DOIs
Publication statusPublished - Apr 2000
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Infectious Diseases

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