The natriuretic peptide family

Kazuwa Nakao, Hiroshi Itoh, Yoshihiko Saito, Masashi Mukoyama, Yoshihiro Ogawa

Research output: Contribution to journalReview articlepeer-review

51 Citations (Scopus)


The natriuretic peptide system is a complicated system comprising at least three endogenous peptides (atrial natriuretic peptide, brain natriuretic peptide and C-type natriuretic peptide) and three receptors [the atrial natriuretic peptide-A receptor (guanylyl cyclase A), the atrial natriuretic peptide-B receptor (guanylyl cyclase B) and the clearance receptor]. The accumulated evidence indicates that this system is implicated in the control of blood pressure, body fluid homeostasis and vascular remodelling as cardiac hormone and local regulator.

Original languageEnglish
Pages (from-to)4-11
Number of pages8
JournalCurrent opinion in nephrology and hypertension
Issue number1
Publication statusPublished - 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Nephrology


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