TY - JOUR
T1 - The incidence of chylous ascites after liver transplantation and the proposal of a diagnostic and management protocol
AU - Matsuura, Toshiharu
AU - Yanagi, Yusuke
AU - Hayashida, Makoto
AU - Takahashi, Yoshiaki
AU - Yoshimaru, Koichiro
AU - Taguchi, Tomoaki
N1 - Funding Information:
The authors thank Brian Quinn for help in the preparation of the manuscript. This research was partly supported by JSPS KAKENHI , Grant Number 15 K10029 .
Publisher Copyright:
© 2017 Elsevier Inc.
PY - 2018/4
Y1 - 2018/4
N2 - Background: No protocol has been established for the diagnosis and management of chylous ascites after liver transplantation (LT). In this study, we retrospectively reviewed our cases of posttransplant chylous ascites (PTCA) and aimed to propose a diagnostic and management protocol. Patients and methods: We retrospectively reviewed the clinical records of 96 LT recipients who underwent LT at our department. The incidence of PTCA and the associated risk factors were analyzed and our protocol for chylous ascites was evaluated. Results: PTCA occurred in 6 (6.3%) patients (mean age: 10.7 ± 11.0 years) at a mean of 10.8 ± 3.6 days after LT. The primary disease in all of PTCA cases was biliary atresia (BA). The periportal lymphadnopathy was an independent risk factor for PTCA. In all cases PTCA successfully resolved according to our protocol. Octreotide was administered in 4 of our 6 PTCA cases. The mean postoperative hospital stay was 40.2 ± 8.4 days, which was similar to that of cases without PTCA. Conclusions: The incidence of PTCA in LT patients, especially in those with BA, is relatively high. Our diagnostic criteria and our management protocol were helpful for patients with refractory ascites after LT. Type of study: Diagnostic test: Level II. Treatment study: Level III.
AB - Background: No protocol has been established for the diagnosis and management of chylous ascites after liver transplantation (LT). In this study, we retrospectively reviewed our cases of posttransplant chylous ascites (PTCA) and aimed to propose a diagnostic and management protocol. Patients and methods: We retrospectively reviewed the clinical records of 96 LT recipients who underwent LT at our department. The incidence of PTCA and the associated risk factors were analyzed and our protocol for chylous ascites was evaluated. Results: PTCA occurred in 6 (6.3%) patients (mean age: 10.7 ± 11.0 years) at a mean of 10.8 ± 3.6 days after LT. The primary disease in all of PTCA cases was biliary atresia (BA). The periportal lymphadnopathy was an independent risk factor for PTCA. In all cases PTCA successfully resolved according to our protocol. Octreotide was administered in 4 of our 6 PTCA cases. The mean postoperative hospital stay was 40.2 ± 8.4 days, which was similar to that of cases without PTCA. Conclusions: The incidence of PTCA in LT patients, especially in those with BA, is relatively high. Our diagnostic criteria and our management protocol were helpful for patients with refractory ascites after LT. Type of study: Diagnostic test: Level II. Treatment study: Level III.
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U2 - 10.1016/j.jpedsurg.2017.06.004
DO - 10.1016/j.jpedsurg.2017.06.004
M3 - Article
C2 - 28625694
AN - SCOPUS:85020888391
SN - 0022-3468
VL - 53
SP - 671
EP - 675
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
IS - 4
ER -