TY - JOUR
T1 - The direct and enantioselective, one-pot, three-component, cross-Mannich reaction of aldehydes
AU - Hayashi, Yujiro
AU - Tsuboi, Wataru
AU - Ashimine, Itaru
AU - Urushima, Tatsuya
AU - Shoji, Mitsuru
AU - Sakai, Ken
PY - 2003/8/11
Y1 - 2003/8/11
N2 - A double-crossed reaction: The use of proline as an organocatalyst enables a one-pot, direct, cross-Mannich reaction to be performed between two different aldehydes and 4-methoxyaniline in a highly syn-diastereo- and enantioselective manner (see scheme).
AB - A double-crossed reaction: The use of proline as an organocatalyst enables a one-pot, direct, cross-Mannich reaction to be performed between two different aldehydes and 4-methoxyaniline in a highly syn-diastereo- and enantioselective manner (see scheme).
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U2 - 10.1002/anie.200351813
DO - 10.1002/anie.200351813
M3 - Article
C2 - 12916046
AN - SCOPUS:0042969372
SN - 1433-7851
VL - 42
SP - 3677
EP - 3680
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 31
ER -