The complex cartography of stem cell commitment

Koichi Akashi, David Traver, Leonard I. Zon

Research output: Contribution to journalShort surveypeer-review

29 Citations (Scopus)


In this issue of Cell, a study by Adolfsson and coworkers (Adolfsson et al., 2005) provides insight into the early lineage commitment events of multipotent hematopoietic stem cells (HSCs). These studies demonstrate the importance of the Flt3 receptor tyrosine kinase as the earliest marker of hematopoietic cell fate commitment in that erythrocyte and megakaryocyte potentials are lost first as HSCs differentiate to lymphocyte progenitors.

Original languageEnglish
Pages (from-to)160-162
Number of pages3
Issue number2
Publication statusPublished - Apr 22 2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Biochemistry,Genetics and Molecular Biology


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