@article{63e8cf17cdd04bac82352a4fec775caf,
title = "The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression",
abstract = "Behavior",
author = "Tadashi Nakagawa and Satoko Hattori and Risa Nobuta and Ryuichi Kimura and Makiko Nakagawa and Masaki Matsumoto and Yuko Nagasawa and Ryo Funayama and Tsuyoshi Miyakawa and Toshifumi Inada and Noriko Osumi and Nakayama, {Keiichi I.} and Keiko Nakayama",
note = "Funding Information: We thank the Wellcome Trust Sanger Institute Mouse Genetics Project (Sanger MGP) and its funders for providing the mutant mouse line (allele: Setd5 tm1a(EUCOMM)Wtsi ). Funding and associated primary phenotypic information may be found at www.sanger.ac.uk/mouseportal . We thank T. Kitamura for pMX-puro and Plat-E cells, T. Sato and laboratory members for discussion, and the Biomedical Research Core of Tohoku University Graduate School of Medicine for technical support. This work was funded by Japan Society for the Promotion of Science (JSPS) KAKENHI grants 15K18365 , 17K14955 , and 19K07837 (to T.N.) and 17H04035 and JP16H06276 (to K.N.); a Grant-in-Aid for Scientific Research on Innovative Areas –Platform for Advanced Technologies and Research Resources ( 16H06276 to T.M.); and in part by the Joint Usage/Research Center for Genes, Brain, and Behavior supported by the Ministry of Education, Culture, Sports, Science and Technology of Japan . Funding Information: We thank the Wellcome Trust Sanger Institute Mouse Genetics Project (Sanger MGP) and its funders for providing the mutant mouse line (allele: Setd5tm1a(EUCOMM)Wtsi). Funding and associated primary phenotypic information may be found at www.sanger.ac.uk/mouseportal. We thank T. Kitamura for pMX-puro and Plat-E cells, T. Sato and laboratory members for discussion, and the Biomedical Research Core of Tohoku University Graduate School of Medicine for technical support. This work was funded by Japan Society for the Promotion of Science (JSPS) KAKENHI grants 15K18365, 17K14955, and 19K07837 (to T.N.) and 17H04035 and JP16H06276 (to K.N.); a Grant-in-Aid for Scientific Research on Innovative Areas–Platform for Advanced Technologies and Research Resources (16H06276 to T.M.); and in part by the Joint Usage/Research Center for Genes, Brain, and Behavior supported by the Ministry of Education, Culture, Sports, Science and Technology of Japan. T.N. designed and performed most of the experiments and cowrote the manuscript. K.N. directed and coordinated the study, oversaw the results, and cowrote the manuscript. M.N. and Y.N. assisted with experiments. S.H. coordinated and assisted with most of the mouse behavioral analyses. R.N. performed polysome analysis. R.K. performed ultrasonic vocalization tests. M.M. performed LC-MS/MS analysis. R.F. performed transcriptomics analysis. T.I. T.M. N.O. and K.I.N. provided advice. All authors discussed the results and commented on the manuscript. The authors declare no competing interests. Publisher Copyright: {\textcopyright} 2020 The Author(s)",
year = "2020",
month = apr,
day = "24",
doi = "10.1016/j.isci.2020.101030",
language = "English",
volume = "23",
journal = "iScience",
issn = "2589-0042",
publisher = "Elsevier Inc.",
number = "4",
}