The antiplatelet aggregation effects of aspirin suppositories

Hiroyuki Nakayasu, Masanobu Maeda, Takao Soda, Kenji Iijima, Manabu Ishimoto, Ichiro Ieiri, Fumie Tabuchi, Kenji Otsubo, Kenji Nakashima

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


To confirm that aspirin suppositories are an effective treatment for acute ischemic stroke, we examined the suppressive effects of 200-mg aspirin suppositories on platelet aggregation. Aspirin suppositories suppressed platelet aggregation induced by ADP or collagen, and the suppression continued for 24 h. There was no significant difference in suppression of platelet aggregation between aspirin administered by suppository and orally given aspirin. These results suggest that aspirin suppositories are a useful treatment for acute ischemic stroke.

Original languageEnglish
Pages (from-to)31-35
Number of pages5
JournalCerebrovascular Diseases
Issue number1
Publication statusPublished - 2003
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine


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