The absolute configuration and total synthesis of korormicin

Hisatoshi Uehara; Tohru Oishi; Kazuhiro Yoshikawa; Kenichi Mochida; Masahiro Hirama

doi:10.1016/S0040-4039(99)01812-2

The absolute configuration and total synthesis of korormicin

Hisatoshi Uehara, Tohru Oishi, Kazuhiro Yoshikawa, Kenichi Mochida, Masahiro Hirama

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

The marine antibiotic korormicin, isolated from the culture filtrate of marine bacterial strain Pseudoalteromonas sp. F-420, specifically inhibits the growth of marine Gram-negative bacteria without affecting terrestrial species. The absolute configuration of korormicin was determined by the combination of a CD exciton chirality method and chemical degradation. Convergent total synthesis of korormicin has been also achieved.

Original language	English
Pages (from-to)	8641-8645
Number of pages	5
Journal	Tetrahedron Letters
Volume	40
Issue number	49
DOIs	https://doi.org/10.1016/S0040-4039(99)01812-2
Publication status	Published - Dec 3 1999
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0040-4039(99)01812-2

Cite this

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abstract = "The marine antibiotic korormicin, isolated from the culture filtrate of marine bacterial strain Pseudoalteromonas sp. F-420, specifically inhibits the growth of marine Gram-negative bacteria without affecting terrestrial species. The absolute configuration of korormicin was determined by the combination of a CD exciton chirality method and chemical degradation. Convergent total synthesis of korormicin has been also achieved.",

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AU - Uehara, Hisatoshi

AU - Oishi, Tohru

AU - Yoshikawa, Kazuhiro

AU - Mochida, Kenichi

AU - Hirama, Masahiro

PY - 1999/12/3

Y1 - 1999/12/3

N2 - The marine antibiotic korormicin, isolated from the culture filtrate of marine bacterial strain Pseudoalteromonas sp. F-420, specifically inhibits the growth of marine Gram-negative bacteria without affecting terrestrial species. The absolute configuration of korormicin was determined by the combination of a CD exciton chirality method and chemical degradation. Convergent total synthesis of korormicin has been also achieved.

AB - The marine antibiotic korormicin, isolated from the culture filtrate of marine bacterial strain Pseudoalteromonas sp. F-420, specifically inhibits the growth of marine Gram-negative bacteria without affecting terrestrial species. The absolute configuration of korormicin was determined by the combination of a CD exciton chirality method and chemical degradation. Convergent total synthesis of korormicin has been also achieved.

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M3 - Article

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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ER -

The absolute configuration and total synthesis of korormicin

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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