Tacrolimus and steroid

Atopic dermatitis is a multifactorial and hereditary cutaneous allergic disease which requires various anti-symptomatic treatments. Therapeutic guidelines indicate standard treatments useful in daily dermatological clinics. The therapeutic mainstay is topical steroid and tacrolimus. Topical tacrolimus not only complement existing treatment options but also overcome some of the drawbacks of topical steroid therapy and fulfil the long-term needs of patients in preventing disease progression. In order to reduce the possible long-term adverse effects and increase the usefulness, it is important to monitor the clinical dose in daily clinics and to create a suitable combination therapy.