Synthetic studies and properties of N-tert-butylaminoxyl nucleosides.

Mariko Aso, Toshiyuki Kaneko, Morihide Nakamura, Yasuhiro Matsui, Noboru Koga, Hiroshi Suemune

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


We synthesized 5-N-tert-butylhydroxylamino-2'-deoxyuridine (9b) via lithium-halogen exchange reaction of sodium salt of 5-iodo-2'-deoxyuridine (8b). This procedure was applicable to synthesis of the corresponding uridine (9a) and N-benzoyl cytidine (13). Obtained 9b was converted into stable aminoxyl (5a) by treatment with Ag2O to study its properties as a novel spin-labeled nucleoside.

Original languageEnglish
Pages (from-to)9-10
Number of pages2
JournalNucleic acids research. Supplement (2001)
Issue number3
Publication statusPublished - 2003

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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