TY - JOUR
T1 - Synthesis of PDMS-based porous materials for biomedical applications
AU - Yabuta, T.
AU - Bescher, E. P.
AU - Mackenzie, J. D.
AU - Tsuru, K.
AU - Hayakawa, S.
AU - Osaka, A.
N1 - Funding Information:
This work was financially supported by the Grant-in-Aid for Scientific Research (B) (2) (11694162), the Ministry of Education, Culture, Sports, Science & Technology, Japan. We are grateful to the SS-NMR Division of the VB Laboratory of Okayama University for the 29Si CP-MAS NMR experiments.
PY - 2003/1
Y1 - 2003/1
N2 - Polydimethylsiloxane (PDMS) and tetraethoxysilane (TEOS)-based porous organically modified silicates (ORMOSILs) for biomedical applications were synthesized through a sol-gel process, using sucrose particles as templates. These materials were characterized by 29Si CP-MAS NMR spectroscopy, thin film X-ray diffraction, and scanning electron microscopy. Their bioactivity was evaluated using a simulated body fluid (SBF) of Kokubo recipe. These materials had a bimodal porous structure with pores of 300-500 μm and 10-50 μm in diameter. NMR showed that the silanol groups of the PDMS chain cross-linked to silica derived from the hydrolysis and condensation of TEOS. The samples containing Ca(II) exhibited apatite deposition on the pore walls within 3 days in SBF.
AB - Polydimethylsiloxane (PDMS) and tetraethoxysilane (TEOS)-based porous organically modified silicates (ORMOSILs) for biomedical applications were synthesized through a sol-gel process, using sucrose particles as templates. These materials were characterized by 29Si CP-MAS NMR spectroscopy, thin film X-ray diffraction, and scanning electron microscopy. Their bioactivity was evaluated using a simulated body fluid (SBF) of Kokubo recipe. These materials had a bimodal porous structure with pores of 300-500 μm and 10-50 μm in diameter. NMR showed that the silanol groups of the PDMS chain cross-linked to silica derived from the hydrolysis and condensation of TEOS. The samples containing Ca(II) exhibited apatite deposition on the pore walls within 3 days in SBF.
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U2 - 10.1023/A:1020772521781
DO - 10.1023/A:1020772521781
M3 - Article
AN - SCOPUS:0037268415
SN - 0928-0707
VL - 26
SP - 1219
EP - 1222
JO - Journal of Sol-Gel Science and Technology
JF - Journal of Sol-Gel Science and Technology
IS - 1-3
ER -