Synthesis of N-methylmorpholine N-(17O-oxide) and N-methylmorpholine 15N-(17O-oxide)

Martina Opietnik; Antje Potthast; Takuya Kitaoka; Thomas Rosenau

doi:10.1002/jlcr.1708

Synthesis of N-methylmorpholine N-(¹⁷O-oxide) and N-methylmorpholine ¹⁵N-(¹⁷O-oxide)

Martina Opietnik, Antje Potthast, Takuya Kitaoka, Thomas Rosenau

Sustainable Bioresources Science

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

N-Methylmorpholine N-(¹⁷O-oxide) and N-methylmorpholine ¹⁵N-(¹⁷O-oxide) were prepared from N-methylmorpholine and ¹⁵N-methylmorpholine by oxidation with H₂ ¹⁷O₂. The facile one-pot procedure provided yields of 82 and 76%, respectively. The labeled hydrogen peroxide was obtained by electrolysis of H₂ ¹⁷O followed by autoxidation of 2-ethylanthraquinol with the molecular oxygen ¹⁷O₂ generated. The compounds serve for mechanistic studies into gold nanoparticle generation in NMMO solution.

Original language	English
Pages (from-to)	78-80
Number of pages	3
Journal	Journal of Labelled Compounds and Radiopharmaceuticals
Volume	53
Issue number	2
DOIs	https://doi.org/10.1002/jlcr.1708
Publication status	Published - Feb 2010

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Biochemistry
Radiology Nuclear Medicine and imaging
Drug Discovery
Spectroscopy
Organic Chemistry

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10.1002/jlcr.1708

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title = "Synthesis of N-methylmorpholine N-(17O-oxide) and N-methylmorpholine 15N-(17O-oxide)",

abstract = "N-Methylmorpholine N-(17O-oxide) and N-methylmorpholine 15N-(17O-oxide) were prepared from N-methylmorpholine and 15N-methylmorpholine by oxidation with H2 17O2. The facile one-pot procedure provided yields of 82 and 76%, respectively. The labeled hydrogen peroxide was obtained by electrolysis of H2 17O followed by autoxidation of 2-ethylanthraquinol with the molecular oxygen 17O2 generated. The compounds serve for mechanistic studies into gold nanoparticle generation in NMMO solution.",

author = "Martina Opietnik and Antje Potthast and Takuya Kitaoka and Thomas Rosenau",

year = "2010",

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doi = "10.1002/jlcr.1708",

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journal = "Journal of Labelled Compounds and Radiopharmaceuticals",

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T1 - Synthesis of N-methylmorpholine N-(17O-oxide) and N-methylmorpholine 15N-(17O-oxide)

AU - Opietnik, Martina

AU - Potthast, Antje

AU - Kitaoka, Takuya

AU - Rosenau, Thomas

PY - 2010/2

Y1 - 2010/2

N2 - N-Methylmorpholine N-(17O-oxide) and N-methylmorpholine 15N-(17O-oxide) were prepared from N-methylmorpholine and 15N-methylmorpholine by oxidation with H2 17O2. The facile one-pot procedure provided yields of 82 and 76%, respectively. The labeled hydrogen peroxide was obtained by electrolysis of H2 17O followed by autoxidation of 2-ethylanthraquinol with the molecular oxygen 17O2 generated. The compounds serve for mechanistic studies into gold nanoparticle generation in NMMO solution.

AB - N-Methylmorpholine N-(17O-oxide) and N-methylmorpholine 15N-(17O-oxide) were prepared from N-methylmorpholine and 15N-methylmorpholine by oxidation with H2 17O2. The facile one-pot procedure provided yields of 82 and 76%, respectively. The labeled hydrogen peroxide was obtained by electrolysis of H2 17O followed by autoxidation of 2-ethylanthraquinol with the molecular oxygen 17O2 generated. The compounds serve for mechanistic studies into gold nanoparticle generation in NMMO solution.

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JO - Journal of Labelled Compounds and Radiopharmaceuticals

JF - Journal of Labelled Compounds and Radiopharmaceuticals

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Synthesis of N-methylmorpholine N-(¹⁷O-oxide) and N-methylmorpholine ¹⁵N-(¹⁷O-oxide)

Abstract

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