Synthesis of multisubstituted furans, pyrroles, and thiophenes via ynolates

Mitsuru Shindo; Yutaka Yoshimura; Maiko Hayashi; Hiroe Soejima; Takashi Yoshikawa; Kenji Matsumoto; Kozo Shishido

doi:10.1021/ol0705200

Synthesis of multisubstituted furans, pyrroles, and thiophenes via ynolates

Mitsuru Shindo, Yutaka Yoshimura, Maiko Hayashi, Hiroe Soejima, Takashi Yoshikawa, Kenji Matsumoto, Kozo Shishido

Department of Fundamental Organic Chemistry

Research output: Contribution to journal › Article › peer-review

93 Citations (Scopus)

Abstract

An efficient synthetic method for the preparation of multisubstituted furans, thiophenes, and pyrroles using ynolates was developed. This novel formal [4 + 1] annulation by C2-C3 and C3-C4 bond formations Includes cycloaddition, cyclization, decarboxylation, and dehydration as key steps.

Original language	English
Pages (from-to)	1963-1966
Number of pages	4
Journal	Organic letters
Volume	9
Issue number	10
DOIs	https://doi.org/10.1021/ol0705200
Publication status	Published - May 10 2007

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol0705200

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AU - Yoshikawa, Takashi

AU - Matsumoto, Kenji

AU - Shishido, Kozo

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AB - An efficient synthetic method for the preparation of multisubstituted furans, thiophenes, and pyrroles using ynolates was developed. This novel formal [4 + 1] annulation by C2-C3 and C3-C4 bond formations Includes cycloaddition, cyclization, decarboxylation, and dehydration as key steps.

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Synthesis of multisubstituted furans, pyrroles, and thiophenes via ynolates

Abstract

All Science Journal Classification (ASJC) codes

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