Synthesis of gene carrier responding with tyrosine kinase 'c-Src' and functional control

Keiko Terada, Yuko Sato, Jun Ohishi, Kenji Kawamura, Jeong Hun Kang, Daisuke Asai, Yoshiki Katayama

    Research output: Contribution to conferencePaperpeer-review


    We designed a gene carrier that can activate the delivered gene in response to the intercellular kinase signal. 'c-Src', which is non-receptor tyrosine kinase, is specifically activated within a cancer cell. We create gene carrier to express a therapeutics gene in response to 'c-Src'. We synthesize polymers that are grafted c-Src substrate peptide as an intercellular signal-response gene carrier. We will discuss the design of c-Src responsive carriers and their abilities for target signal specific gene regulation.

    Original languageEnglish
    Number of pages1
    Publication statusPublished - 2006
    Event55th SPSJ Annual Meeting - Nagoya, Japan
    Duration: May 24 2006May 26 2006


    Other55th SPSJ Annual Meeting

    All Science Journal Classification (ASJC) codes

    • General Engineering


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