Synthesis of chiral [60]fullerene-steroid bisadducts using steroid templates

Tsutomu Ishi-i, Seiji Shinkai

Research output: Contribution to journalArticlepeer-review

40 Citations (Scopus)


The double [4+2] cycloadditions between [60]fullerene and steroid- appended dibenzoates 7 and 8, the reaction sites of which were controlled by diols in chiral template molecules, afforded [60]fullerene-steroid bisadducts 11 and 12 regio- and chiroselectively. CD spectroscopic studies of 11 and 12 indicated that the magnitude of the cotton effects changes reflecting the chiral structure of the steroid moiety in 11 and 12.

Original languageEnglish
Pages (from-to)12515-12530
Number of pages16
Issue number43
Publication statusPublished - Oct 22 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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