Synthesis of bioactive organic-inorganic hybrids with γ-methacryloxypropyltrimethoxysilane

Takeshi Yabuta, Kanji Tsuru, Satoshi Hayakawa, Chikara Ohtsuki, Akiyoshi Osaka

Research output: Contribution to journalConference articlepeer-review

27 Citations (Scopus)


Bioactive organic-inorganic hybrids were synthesized through sol-gel processing starting from γ-methacryloxypropyltrimethoxysilane. NMR-spectroscopic studies showed the presence of silanol groups (Si-OH) and Si-O-Si bonds. In vitro tests of the hybrids for bioactivity with a simulated body fluid (Kokubo solution) indicated that only calcium-containing hybrids could form apatite on their surfaces. Thus the presence of calcium ions was no less important to deposit apatite than the formation of silanol groups or Si-O-Si bonds.

Original languageEnglish
Pages (from-to)745-748
Number of pages4
JournalJournal of Sol-Gel Science and Technology
Issue number1-3
Publication statusPublished - Dec 2000
Externally publishedYes
Event10th International Workshop pn Glass and Ceramics, Hybrids and Nanocomposites from Gels - Yokohama, Jpn
Duration: Sept 20 1999Sept 24 1999

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Biomaterials
  • Condensed Matter Physics
  • Materials Chemistry


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